Tritten J J, Perret C, Zografos L, Gailloud C
Hôpital Ophtalmique, Lausanne, Suisse.
Ophtalmologie. 1990 Jan-Feb;4(1):40-2.
Rabbit ciliary body has been irradiated by accelerated proton beam. 24 animals have received on 20 and 40% of the total surface of ciliary body 45 and 60 Gy. We could confirm the very good precision of proton beam irradiation. No complication was noticed on slit lamp examination. The light microscope examination revealed haemorrhages, lymphocytes, plasma cells and histiocytes infiltration, late fibrosis and severe capillary alterations. The electron microscope examination showed a frank difference of radiosensitivity of the epithelial layers and a presumed partial rupture of the blood-aqueous barrier.
兔睫状体已接受加速质子束照射。24只动物分别接受了睫状体总表面积20%和40%的45 Gy和60 Gy照射。我们能够证实质子束照射的精度非常高。裂隙灯检查未发现并发症。光学显微镜检查显示有出血、淋巴细胞、浆细胞和组织细胞浸润、晚期纤维化以及严重的毛细血管改变。电子显微镜检查显示上皮层的放射敏感性存在明显差异，并且推测血-房水屏障有部分破裂。
