Department of Chemistry, Kakatiya University, Warangal-506009, Andhra Pradesh, India.
Fitoterapia. 2011 Oct;82(7):1039-43. doi: 10.1016/j.fitote.2011.06.011. Epub 2011 Jul 2.
Phytochemical investigation of Caralluma adscendens var. gracilis and Caralluma pauciflora (Asclepiadaceae) whole plant extracts allowed to isolate one pregnane glycoside and two pregnanes characterized as 12β,20-O-dibenzoyl-5α,6-dihydrosarcostin β-oleandropyranosyl-(1→4)-β-cymaropyranosyl-(1→4)-β-digitoxypyranosyl-(1→4)-β-cymaropyranosyl-(1→4)-β-cymaropyranoside (1), 12β-O-benzoyl-3β,11α,14β,20R-pentahydroxy-pregn-5-ene (2), and 11α-O-benzoyl-3β,12β,14β,20R-pentahydroxy-pregn-5-ene (3), respectively. Their structural characterization was obtained on the basis of extensive NMR spectral studies. Three known pregnane glycosides along with lupeol and β-sitosterol were also isolated and characterized.
对 Caralluma adscendens var. gracilis 和 Caralluma pauciflora(夹竹桃科)全植物提取物进行植物化学研究,得以分离出一种孕烷糖苷和两种孕烷,分别鉴定为 12β,20-O-二苯甲酰基-5α,6-二氢 sarcostin β-橙皮糖苷基-(1→4)-β-芹糖基-(1→4)-β-葡萄糖基-(1→4)-β-橙皮糖苷基-(1→4)-β-橙皮糖苷(1)、12β-O-苯甲酰基-3β,11α,14β,20R-五羟基孕-5-烯(2)和 11α-O-苯甲酰基-3β,12β,14β,20R-五羟基孕-5-烯(3)。基于广泛的 NMR 光谱研究确定了它们的结构特征。此外,还分离并鉴定了三种已知的孕烷糖苷以及羽扇豆醇和β-谷甾醇。