Baturin V A, Shchetinin E V, Arushanian E B
Zh Vyssh Nerv Deiat Im I P Pavlova. 1990 Jul-Aug;40(4):673-80.
By the time course of forced swimming all rats may be separated in several groups with typical patterns of circadian motility. In case when active swimming movements and reduced immobility predominated, invert type of daily chronogram with low activity at the night hours and high sensitivity to chronic imipramine treatment were observed. Considerable immobility correlates with clear circadian rhythm and weak response to antidepressant. It is suggested that rhythmical pattern of the forced swimming may be used as predicator of circadian motility type.
在强迫游泳的整个过程中,所有大鼠可能会被分为几组,每组具有典型的昼夜活动模式。当主动游泳运动占主导且不动时间减少时,会观察到倒置型的日活动图表,夜间活动量低,对慢性丙咪嗪治疗的敏感性高。大量的不动时间与清晰的昼夜节律以及对抗抑郁药的微弱反应相关。有人认为,强迫游泳的节律模式可作为昼夜活动类型的预测指标。