Seracchioli R, Mabrouk M, De Iaco P, Facchini C, Vicenzi C, Di Donato N, Montanari G, Venturoli S
Centro di Chirurgia, Ginecologica Mini-invasiva, Unità di Ginecolocia e Medicina Riproduttiva Ospedale S. Orsola-Malpighi, Università di Bologna, Italia.
Minerva Ginecol. 2011 Aug;63(4):315-23.
The aim of this study was to investigate the feasibility and safety of laparoscopic staging of overweight women with endometrial cancer and to compare the surgical outcomes among these patients with those managed by laparotomy.
This was a retrospective analysis (Canadian Task-force Classification II-3). We reviewed operative and hospital records of 70 patients with a body mass index >25 kg/m2 who underwent surgical treatment for endometrial cancer between 2001 and 2008. Thirty-five patients treated laparoscopically were compared to an equivalent group of patients treated by laparotomy. Operative and postoperative variables were afterwards assessed.
Women in laparoscopic group had a significantly lower blood loss (median, 25th-75th percentiles: 1.2, 0.8-2.0 in laparoscopic versus 1.8, 1.0-2.8 in laparotomic group, P<0.05). No differences between both group in terms of operative time (median, 25th-75th percentiles: 165 min, 130-183 in laparoscopic versus 135 min, 110-170 in laparotomic; P>0.05) and mean number of pelvic and para-aortic lymph nodes removed (22 ± 8.4 versus 24 ± 6.2 and 9.2 ± 2.5 versus 9.3 ± 5 respectively; P>0.05). Length of urethral catheter and hospital stay were statistically higher in laparotomic group (two days versus three days; four days versus seven days respectively; P<0.05).
Laparoscopic surgery in overweight women with endometrial cancer had equivalent surgical staging than women operated by laparotomy. With regard to postsurgical variables, overweight women who underwent laparoscopic surgery had better results than those treated by laparotomy.
本研究旨在探讨对超重子宫内膜癌女性进行腹腔镜分期的可行性和安全性,并比较这些患者与接受开腹手术患者的手术结局。
这是一项回顾性分析(加拿大工作组分类II-3)。我们回顾了2001年至2008年间70例体重指数>25kg/m²的子宫内膜癌手术治疗患者的手术和住院记录。将35例行腹腔镜手术治疗的患者与同等数量的开腹手术治疗患者进行比较。随后评估手术和术后变量。
腹腔镜组女性的失血量显著更低(中位数,第25-75百分位数:腹腔镜组为1.2,0.8-2.0;开腹组为1.8,1.0-2.8,P<0.05)。两组在手术时间(中位数,第25-75百分位数:腹腔镜组为165分钟,130-183;开腹组为135分钟,110-170;P>0.05)以及盆腔和腹主动脉旁淋巴结切除的平均数量方面无差异(分别为22±8.4对24±6.2以及9.2±2.5对9.3±5;P>0.05)。开腹组的导尿管留置时间和住院时间在统计学上更长(分别为2天对3天;4天对7天;P<0.05)。
超重子宫内膜癌女性的腹腔镜手术与开腹手术具有同等的手术分期效果。在术后变量方面,接受腹腔镜手术的超重女性比接受开腹手术的女性效果更好。