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癌症患者用槲寄生提取物（iscador）治疗的生活质量和相关维度：荟萃分析。

Quality of life and related dimensions in cancer patients treated with mistletoe extract (iscador): a meta-analysis.

机构信息

Center for Integrative Medicine, Faculty of Health, University of Witten/Herdecke, Gerhard-Kienle-Weg 4, 58239 Herdecke, Germany.

出版信息

Evid Based Complement Alternat Med. 2012;2012:219402. doi: 10.1155/2012/219402. Epub 2011 Jun 14.

DOI:10.1155/2012/219402
PMID:21747894
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3124023/
Abstract

Objectives. The aim of this meta-analysis was to determine the effectiveness of the fermented plant extract Iscador, produced from the white-berry European mistletoe, in the treatment of patients with cancer with respect to quality-of-life- (QoL-) associated measures. Methods. We searched databases such as PubMed/Medline, Excerpta Medica Database (EMBASE), CAMbase, and other for controlled clinical studies on parameters associated with QoL. Outcome data were extracted and converted into standardized mean differences and their standard errors. Results. Thirteen prospective and controlled studies which met the inclusion/exclusion criteria reported positive effects in favor of the Iscador application. A random-effect meta-analysis estimated the overall treatment effect at standardized mean difference = 0.56 (CI: 0.41 to 0.71, P < .0001). However, the methodological quality of the studies was poor. Conclusions. The analyzed studies give some evidence that Iscador treatment might have beneficial short-time effects on QoL-associated dimensions and psychosomatic self-regulation.

摘要

目的

本荟萃分析旨在确定源自欧洲白浆果槲寄生的发酵植物提取物 Iscador 对癌症患者生活质量（QoL）相关指标的治疗效果。

方法

我们在 PubMed/Medline、Excerpta Medica Database（EMBASE）、CAMbase 和其他数据库中搜索与 QoL 相关的参数的对照临床试验。提取并将结局数据转换为标准化均数差及其标准误。

结果

符合纳入/排除标准的 13 项前瞻性和对照研究报告了 Iscador 应用的阳性效果。随机效应荟萃分析估计总体治疗效果为标准化均数差=0.56（CI：0.41 至 0.71，P<0.0001）。然而，研究的方法学质量较差。

结论

分析研究表明，Iscador 治疗可能对 QoL 相关维度和身心自我调节具有有益的短期效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cca/3124023/e87cfda13783/ECAM2012-219402.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cca/3124023/196bc8a414ee/ECAM2012-219402.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cca/3124023/24b60b7ecdbc/ECAM2012-219402.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cca/3124023/64a6b1d36088/ECAM2012-219402.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cca/3124023/40304c550ef6/ECAM2012-219402.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cca/3124023/e87cfda13783/ECAM2012-219402.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cca/3124023/196bc8a414ee/ECAM2012-219402.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cca/3124023/24b60b7ecdbc/ECAM2012-219402.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cca/3124023/64a6b1d36088/ECAM2012-219402.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cca/3124023/40304c550ef6/ECAM2012-219402.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6cca/3124023/e87cfda13783/ECAM2012-219402.005.jpg

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