Department of Biology, Eastern Connecticut State University, Willimantic, USA.
Int Rev Cell Mol Biol. 2011;289:149-209. doi: 10.1016/B978-0-12-386039-2.00005-5.
Many types of eukaryotic cells can fuse together as part of their normal developmental program or life cycle. This review describes a diverse set of examples of such cell types and focuses attention on several molecules that appear intimately involved in the process of plasma membrane merger that lies at the crux of every cell-fusion event. Some of these examples come from experimental systems where the discovery of molecules essential for cell fusion is sped by the approachability of the experimental organism itself. In other cases, especially in the many fusing human cell types, the molecular players in cell-cell membrane fusion are still to be discovered.
许多类型的真核细胞可以融合在一起，这是它们正常发育程序或生命周期的一部分。本文描述了一系列不同类型的此类细胞，并重点介绍了几种似乎密切参与位于每个细胞融合事件核心的质膜融合过程的分子。这些例子中的一些来自实验系统，其中实验生物本身的可接近性加速了对细胞融合必不可少的分子的发现。在其他情况下，特别是在许多融合的人类细胞类型中，细胞-细胞膜融合的分子参与者仍有待发现。
