Department of Radiology and Research Institute of Biomedical Science, Konkuk University School of Medicine, Seoul, South Korea.
Br J Radiol. 2011 Aug;84(1004):691-7. doi: 10.1259/bjr/27559204.
The purpose of this study was to assess the technical feasibility and local efficacy of biplane fluoroscopy-guided percutaneous radiofrequency (RF) ablation combined with transcatheter arterial chemoembolisation (TACE) for hepatocellular carcinoma (HCC).
Our retrospective study was approved by the institutional review board and informed consent was waived. 18 patients with 19 HCCs (mean 2.5 cm diameter; range 2-4.2 cm) were treated with percutaneous RF ablation combined with TACE. After segmental TACE, 18 (95%) of 19 HCCs were visible on fluoroscopy. Shortly (median 2 days; range 1-4 days) after TACE, percutaneous RF ablation was performed under real-time biplane fluoroscopic guidance. We evaluated major complications, rate of technical success at immediate post-RF ablation CT images and local tumour progression at follow-up CT images.
Major complication was not observed in any patients. Technical success was achieved for all 18 visible HCCs. During the follow-up period (median 20 months; range 5-30 months), no local tumour progression was found.
Biplane fluoroscopy-guided RF ablation combined with TACE is technically feasible and effective for treatment of HCC.
本研究旨在评估双平面透视引导下经皮射频（RF）消融联合经导管动脉化疗栓塞（TACE）治疗肝细胞癌（HCC）的技术可行性和局部疗效。
本回顾性研究获得了机构审查委员会的批准，并豁免了知情同意。18 例 19 个 HCC（平均直径 2.5cm；范围 2-4.2cm）患者接受了经皮 RF 消融联合 TACE 治疗。在节段性 TACE 后，19 个 HCC 中有 18 个（95%）在透视下可见。在 TACE 后（中位数 2 天；范围 1-4 天）短期内，在实时双平面透视引导下进行经皮 RF 消融。我们评估了主要并发症、即刻 RF 消融后 CT 图像的技术成功率和随访 CT 图像的局部肿瘤进展情况。
无患者出现重大并发症。所有 18 个可见 HCC 均达到技术成功。在随访期间（中位数 20 个月；范围 5-30 个月），未发现局部肿瘤进展。
双平面透视引导下 RF 消融联合 TACE 治疗 HCC 是一种技术可行且有效的方法。
