Tane Shinya, Tanaka Yugo, Tauchi Syunsuke, Uchino Kazuya, Nakai Reiko, Yoshimura Masahiro
Department of Thoracic Surgery, Hyogo Cancer Center, 13-70 Kitaouji-cho, Akashi 673-8558, Japan.
Gen Thorac Cardiovasc Surg. 2011 Jul;59(7):503-6. doi: 10.1007/s11748-010-0710-z. Epub 2011 Jul 14.
Angiosarcoma is a rare neoplasm, accounting for only 1%-2% of all sarcomas. It occurs most frequently in the skin and soft tissue and rarely in the thoracic region. To our knowledge, a mediastinal angiosarcoma is extremely rare. We report on the surgical resection of a rare case of giant epithelioid angiosarcoma originating in the anterior mediastinum, followed by six courses of adjuvant chemotherapy (doxorubicin + ifosfamide). The patient is alive and asymptomatic 1 year after surgery. As the prognosis for unresectable cases is generally dismal, surgical resection and adjuvant therapy can be an option for mediastinal angiosarcoma.
血管肉瘤是一种罕见的肿瘤，仅占所有肉瘤的1%-2%。它最常发生于皮肤和软组织，很少发生于胸部区域。据我们所知，纵隔血管肉瘤极为罕见。我们报告了一例起源于前纵隔的罕见巨大上皮样血管肉瘤的手术切除病例，随后进行了六个疗程的辅助化疗（多柔比星+异环磷酰胺）。患者术后1年存活且无症状。由于不可切除病例的预后通常很差，手术切除和辅助治疗可能是纵隔血管肉瘤的一种选择。
