使用动态F-氟化物PET评估骨移植的参数图像。
Parametric Images in Assessing Bone Grafts Using Dynamic F-Fluoride PET.
作者信息
Wen Lingfeng, Eberl Stefan, Feng David Dagan, Stalley Paul, Huang Gang, Fulham Michael J
机构信息
Department of PET and Nuclear Medicine, Royal Prince Alfred Hospital, Sydney, NSW 2050, Australia.
出版信息
Int J Mol Imaging. 2011;2011:189830. doi: 10.1155/2011/189830. Epub 2011 May 22.
The early identification of graft failure would improve patient management. (18)F-fluoride is a suitable tracer for quantifying bone metabolism. Performance of parametric images constructed by Patlak graphical analysis (PGA) with various time periods was evaluated in the analysis of dynamic (18)F-fluoride PET studies of eight patients with fibula bone grafts after limb salvage surgery. The PGA parametric image approach tended to underestimate influx rate. The linear portion of PGA analysis was found to be from 10 to 50 min. It shows promise in providing a quantitative assessment of the viability of bone grafts.
早期识别移植失败将改善患者管理。（18）F-氟化物是一种用于量化骨代谢的合适示踪剂。在对八名保肢手术后接受腓骨移植的患者进行动态（18）F-氟化物PET研究的分析中，评估了使用不同时间段通过Patlak图形分析（PGA）构建的参数图像的性能。PGA参数图像方法往往会低估流入率。发现PGA分析的线性部分为10至50分钟。它在提供骨移植活力的定量评估方面显示出前景。
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