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针刺对比昂丹司琼用于剖宫产术中及术后恶心呕吐的效果。

Effect of acupuncture on nausea and/or vomiting during and after cesarean section in comparison with ondansetron.

机构信息

Department of Anesthesiology, Faculty of Medicine, Mansoura University, Mansoura, Egypt.

出版信息

J Anesth. 2011 Oct;25(5):698-703. doi: 10.1007/s00540-011-1198-0. Epub 2011 Jul 15.

Abstract

PURPOSE

Acupuncture has been used for the management of postoperative nausea and vomiting (PONV). This study compared the effect of electrical acustimulation with ondansetron for preventing intraoperative and postoperative emetic symptoms and improving patient satisfaction.

METHODS

After gaining ethical approval, 450 parturients scheduled for elective cesarean delivery were randomly allocated to receive either electrical stimulation using P6 acupoint (pericardium 6) bilaterally for 30 min before spinal anesthesia (group III; n = 150), or 4 mg ondansetron 30 min before spinal anesthesia (group II; n = 150), or placebo (group II; n = 150). Nausea and vomiting were evaluated and recorded intraoperatively and postoperative for 24 h by an independent anesthetist.

RESULTS

The three groups were not significantly different with respect to intraoperative ephedrine dose and duration of surgery. Nausea and vomiting occurred statistically significantly less often in the active treatment groups (II, III) during operation and for 6 h postoperatively. There was no statistically significant difference between the groups in the incidence of nausea and vomiting from 6 to 24 h postoperatively. Patient satisfaction with PONV control was higher with the active treatment groups compared with group I.

CONCLUSION

Electrical acustimulation is comparable to ondansetron in prevention of PONV during and after cesarean delivery under spinal anesthesia and in improving patient satisfaction.

摘要

目的

针刺已被用于术后恶心呕吐(PONV)的治疗。本研究比较了电刺激双侧内关穴(心包经 6 穴)与昂丹司琼预防术中及术后呕吐症状和提高患者满意度的效果。

方法

在获得伦理批准后,450 名计划行择期剖宫产的产妇被随机分配,分别接受电刺激(30 分钟)双侧内关穴(组 III;n=150)、30 分钟前给予昂丹司琼 4mg(组 II;n=150)或安慰剂(组 II;n=150)。由一名独立麻醉师评估和记录术中及术后 24 小时的恶心和呕吐情况。

结果

三组在术中麻黄碱剂量和手术持续时间方面无显著差异。在术中及术后 6 小时,电刺激组(II、III)恶心和呕吐的发生率明显较低。在术后 6-24 小时,三组间恶心和呕吐的发生率无统计学差异。与组 I 相比,电刺激组的患者对 PONV 控制的满意度更高。

结论

电刺激在预防椎管内麻醉下剖宫产术中及术后 PONV 方面与昂丹司琼相当,并且可以提高患者满意度。

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