Chen Zhe, Tao Zezhang, Deng Yuqin, Xu Yu, Kong Yonggang, Xiao Bokui
Department of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060,China.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2011 Apr;25(8):339-41, 346.
To investigate the positive rates of some allergens in different age groups of allergic rhinitis patients, and to analyze the relationship between serum specific immunoglobulin E(sIgE) and total immunoglobulin E(IgE).
Six hundred and fifty-three patients with allergic rhinitis, tested by AllergyScreen system, were enrolled in our research.
The positive rate of sIgE in all patients was 85.5%. The positive rate of dust mite was the highest with the result of 76.3%, and the positive rate of feline or dogs hair was the lowest of 20.3%. The statistical significance of different positive rate of some allergens were found in the different age groups. All the patients were divided into two groups, one was younger than 18 years old group, which including 18 years old and another was older than 18 years old group. Except Mx, the positive rate of other allergens existed statistical difference. The level of serum total IgE could not reflect the positive rate of sIgE completely.
It is an effective and reliable method of the diagnosis of allergic rhinitis to combine the analysis of total serum IgE and sIgE levels with patients clinical manifestations. Different strategies should be employed for the prevention and treatment of allergic rhinitis according to their ages.
探讨变应性鼻炎患者不同年龄组中某些变应原的阳性率，并分析血清特异性免疫球蛋白E（sIgE）与总免疫球蛋白E（IgE）之间的关系。
选取653例变应性鼻炎患者，采用AllergyScreen系统进行检测，纳入本研究。
所有患者中sIgE的阳性率为85.5%。尘螨的阳性率最高，为76.3%，猫毛或狗毛的阳性率最低，为20.3%。不同年龄组中某些变应原的阳性率存在统计学差异。所有患者分为两组，一组为18岁及以下组，另一组为18岁以上组。除Mx外，其他变应原的阳性率存在统计学差异。血清总IgE水平不能完全反映sIgE的阳性率。
将血清总IgE和sIgE水平分析与患者临床表现相结合是诊断变应性鼻炎的有效且可靠的方法。应根据变应性鼻炎患者的年龄采取不同的防治策略。
