[血清特异性IgE检测与变应性鼻炎皮肤点刺试验的相关性]

[The correlation of serum specific IgE detection and skin prick test in allergic rhinitis].

作者信息

Zhang Yinghong, Zhu Li, Zhang Ke, Zhang Ping, Song Yu, Du Chen, Duan Qingchuan, Ma Furong

机构信息

Department of Otolaryngology, Peking University Third Hospital, Beijing, 100191, China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2013 Jan;27(2):75-7, 80.

PMID:23650705

Abstract

OBJECTIVE

To investigate the correlation between serum specific immunoglobin E(sIgE) and skin prick test(SPT) and their differences of the positive rate.

METHOD

One hundred and nine patients with allergic rhinitis were detected the serum slgE. The patients had positive symptoms and signs, positive SPT results with at least one allergen.

RESULT

Specific IgE and SPT results of Dp,Df and Artemisia showed a positive correlation (r = 0.520, 0.4413, 0.764, P < 0.01). sIgE positive rates were 55.0%, 54.1% and 17.4% for Dp, Df and Artemisia respectively, whereas SPT positive rates were 68.8%,79.8% and 27.5% respectively. The difference between the positive rates of the sIgE and SPT was significant (chi2 = 27.93,18. 20,60. 60, are P< 0.01).

CONCLUSION

There was a good correlation between specific IgE and SPT. SPT is more sensitive than sIgE, but SPT can not substitute for slgE,vice versa.

摘要

目的

探讨血清特异性免疫球蛋白E（sIgE）与皮肤点刺试验（SPT）之间的相关性及其阳性率的差异。

方法

对109例变应性鼻炎患者检测血清sIgE。这些患者有阳性症状和体征，且SPT结果显示对至少一种变应原呈阳性。

结果

粉尘螨、屋尘螨和艾蒿的特异性IgE与SPT结果呈正相关（r = 0.520、0.4413、0.764，P < 0.01）。粉尘螨、屋尘螨和艾蒿的sIgE阳性率分别为55.0%、54.1%和17.4%，而SPT阳性率分别为68.8%、79.8%和27.5%。sIgE与SPT阳性率之间的差异有统计学意义（χ2 = 27.93、18.20、60.60，P均< 0.01）。