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脉络康胶囊联合低分子肝素钙(苏比林)治疗骨折术后下肢深静脉血栓形成(DVT)的临床观察

[Clinical observation of lower extremity deep venous hrombosis (DVT) postoperative fracture treated by Maixuekang capsule and low molecular heparin calcium (Subilin)].

作者信息

Liu Qingfeng, Chang Yijie

机构信息

Zhengzhou Orthopaedics Hospital, Zhengzhou 450052, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2011 Apr;36(7):945-8.

PMID:21761740
Abstract

OBJECTIVE

To observe the clinical curative effects of lower extremity deep venous thrombosis (DVT) postoperative fracture treated by maixuekang capsule and low molecular heparin calcium (Subilin).

METHOD

From Feb 2008 to Apr 2010, 214 cases of lower extremity DVT postoperative fracture were randomly divided into experimental group and control group. The 107 cases of them were treated by maixuekang capsule based on the comprehensive treatment.

RESULT

The 89 cases were cured and improved in the observation group, but 18 cases were ineffectiveness. The 66 cases were cured and improved in the control group, but 41 cases were ineffectiveness. Maixuekang capsule group had 83. 18% (89/107) total effective rate and 61.68% (66/107) total effective rate in the control group. There was significant difference between the two groups (P < 0.05). After the treatment, the perimeter between the suffered limb and the healthy one was significantly reduced, the blood rheology examination had been improved significantly. There was also significant difference between the two groups (P < 0.05).

CONCLUSION

Maixuekang capsule for lower extremity deep vein thrombasis has good effect It has both thrombolytic and anticoagulant effects for lower extremity DVT postoperative fracture treated by maixuekang capsule and low molecular heparin calcium (Subilin). It's a recommended treatment.

摘要

目的

观察脉血康胶囊联合低分子肝素钙(苏比利)治疗下肢深静脉血栓形成(DVT)术后骨折的临床疗效。

方法

选取2008年2月至2010年4月期间下肢DVT术后骨折患者214例,随机分为实验组和对照组。实验组107例在综合治疗基础上加用脉血康胶囊治疗。

结果

观察组89例治愈好转,18例无效;对照组66例治愈好转,41例无效。脉血康胶囊组总有效率为83.18%(89/107),对照组总有效率为61.68%(66/107),两组比较差异有统计学意义(P<0.05)。治疗后患肢与健肢周径差明显减小,血液流变学指标明显改善,两组比较差异有统计学意义(P<0.05)。

结论

脉血康胶囊治疗下肢深静脉血栓形成疗效良好,脉血康胶囊联合低分子肝素钙(苏比利)治疗下肢DVT术后骨折具有溶栓和抗凝双重作用,值得推荐。

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