GlaxoSmithKline Consumer Healthcare, Weybridge, Surrey, UK.
Int Dent J. 2011 Aug;61 Suppl 3(Suppl 3):28-32. doi: 10.1111/j.1875-595X.2011.00046.x.
To introduce a variable which directly measures maintenance of gingival health.
The maintenance of gingival health index (MGHI) is based on the change in score at each tooth site compared to a reference visit for a clinical index (eg MGI or BI). For a subject the number of sites that (1) improve-NDEC, (2) show no change-NNOCHG or (3) worsen-NINC in score are determined. Then the MGHI for a subject is defined as (NDEC+NNOCHNG)/NINC.
This method was applied to two clinical studies and both studies demonstrated significantly better maintenance of gingival health in those subjects who received the experimental 0.1% w/w o-cymen-5-ol/ 0.6% w/w ZnCl2 dentifrice compared to the 0.204% w/w sodium fluoride control dentifrice based on a gingival and a bleeding clinical index.
The MGHI is a useful measure to assess the maintenance of gingival health. It is very applicable to the maintenance of gingival health study designs as it directly looks at a measurement of maintaining the health of tooth sites. It also provides a meaningful measure of the relative effectiveness of dentifrice products to the dental practitioner.
引入一个可直接衡量牙龈健康维护情况的变量。
牙龈健康维护指数(MGHI)基于每个牙位与参考就诊时临床指数(如 MGI 或 BI)评分的变化。对于一个受试者,确定(1)改善-NDEC、(2)无变化-NNOCHG 或(3)恶化-NINC 的牙位数量。然后,将受试者的 MGHI 定义为(NDEC+NNOCHNG)/NINC。
该方法应用于两项临床研究,均表明接受实验性 0.1%w/w 邻伞花烃-5-醇/0.6%w/wZnCl2 牙膏的受试者在牙龈和出血临床指数方面,其牙龈健康维护情况明显优于接受 0.204%w/w 氟化钠对照牙膏的受试者。
MGHI 是评估牙龈健康维护情况的有用指标。它非常适用于牙龈健康维护研究设计,因为它直接关注牙位健康的维持情况。它还为牙医提供了衡量牙膏产品相对有效性的有意义指标。