Xing Xin, Liao Yongde, Tang Hexiao, Chen Guang, Ju Sheng, You Liangkun
Department of General Thoracic Surgery, Huazhong University of Science and Technology, Wuhan 430030, China.
Zhongguo Fei Ai Za Zhi. 2011 Jul;14(7):625-30. doi: 10.3779/j.issn.1009-3419.2011.07.12.
Lung cancer has been viewed as the most common malignant cancer with high incidence, mortality and poor survival all over the world. A lot of investigations indicated there are significant gender-associated differences in lung cancer in several characteristics such as epidemiology, pathology, clinical outcome and prognosis. The insight into these differences may help to clarify the gender-associated characteristics of lung cancer, and to drawn out new approach for treatment and prevent of lung cancer depending on gender-associated characteristics. Furthermore, study on mechanism of gender-associated characteristics may even help to illuminate the pathogenesis of lung cancer.
肺癌一直被视为全球最常见的恶性肿瘤,其发病率、死亡率高,生存率低。大量研究表明,肺癌在流行病学、病理学、临床结局和预后等几个特征方面存在显著的性别相关差异。深入了解这些差异可能有助于阐明肺癌的性别相关特征,并根据性别相关特征制定新的肺癌治疗和预防方法。此外,对性别相关特征机制的研究甚至可能有助于阐明肺癌的发病机制。