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[肺癌的性别相关差异及机制]

[Gender-associated differences of lung cancer and mechanism].

作者信息

Xing Xin, Liao Yongde, Tang Hexiao, Chen Guang, Ju Sheng, You Liangkun

机构信息

Department of General Thoracic Surgery, Huazhong University of Science and Technology, Wuhan 430030, China.

出版信息

Zhongguo Fei Ai Za Zhi. 2011 Jul;14(7):625-30. doi: 10.3779/j.issn.1009-3419.2011.07.12.

DOI:10.3779/j.issn.1009-3419.2011.07.12
PMID:21762635
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6000266/
Abstract

Lung cancer has been viewed as the most common malignant cancer with high incidence, mortality and poor survival all over the world. A lot of investigations indicated there are significant gender-associated differences in lung cancer in several characteristics such as epidemiology, pathology, clinical outcome and prognosis. The insight into these differences may help to clarify the gender-associated characteristics of lung cancer, and to drawn out new approach for treatment and prevent of lung cancer depending on gender-associated characteristics. Furthermore, study on mechanism of gender-associated characteristics may even help to illuminate the pathogenesis of lung cancer.

摘要

肺癌一直被视为全球最常见的恶性肿瘤,其发病率、死亡率高,生存率低。大量研究表明,肺癌在流行病学、病理学、临床结局和预后等几个特征方面存在显著的性别相关差异。深入了解这些差异可能有助于阐明肺癌的性别相关特征,并根据性别相关特征制定新的肺癌治疗和预防方法。此外,对性别相关特征机制的研究甚至可能有助于阐明肺癌的发病机制。

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Lung cancer after heart transplantation: results from a large multicenter registry.心脏移植后肺癌:来自大型多中心注册研究的结果。
Am J Transplant. 2011 May;11(5):1035-40. doi: 10.1111/j.1600-6143.2011.03515.x.
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Epidemiology of lung cancer in women: risk factors, survival, and screening.女性肺癌的流行病学:危险因素、生存和筛查。
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[Mortality time trends and the incidence and mortality estimation and projection for lung cancer in China].[中国肺癌死亡率的时间趋势及发病率、死亡率估计与预测]
Zhongguo Fei Ai Za Zhi. 2005 Aug 20;8(4):274-8. doi: 10.3779/j.issn.1009-3419.2005.04.05.
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Cancer statistics, 2010.癌症统计数据,2010 年。
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Prevalence of human papillomavirus 16/18/33 infection and p53 mutation in lung adenocarcinoma.肺腺癌中人乳头瘤病毒 16/18/33 感染和 p53 突变的流行情况。
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Nuclear and cytoplasmic expressions of ERβ1 and ERβ2 are predictive of response to therapy and alters prognosis in familial breast cancers.核和细胞质中 ERβ1 和 ERβ2 的表达可预测家族性乳腺癌对治疗的反应,并改变其预后。
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Human papilloma virus and female lung adenocarcinoma.人乳头瘤病毒与女性肺腺癌。
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Gender difference in treatment outcomes in patients with stage III non-small cell lung cancer receiving concurrent chemoradiotherapy.接受同步放化疗的 III 期非小细胞肺癌患者治疗结果的性别差异。
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W V Med J. 2009 Jul-Aug;105(4):18-22.