环境表面甲型肝炎病毒的化学消毒
Chemical disinfection of hepatitis A virus on environmental surfaces.
作者信息
Mbithi J N, Springthorpe V S, Sattar S A
机构信息
Department of Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ontario, Canada.
出版信息
Appl Environ Microbiol. 1990 Nov;56(11):3601-4. doi: 10.1128/aem.56.11.3601-3604.1990.
Abstract
Hepatitis A virus disinfection was assessed on contaminated stainless-steel disks. Ten microliters of fecally suspended hepatitis A virus was deposited on the center of each disk, dried for 20 min, and then covered with 20 microliters of the test product for 1 min. Of the 20 formulations tested, only 2% glutaraldehyde, a quaternary ammonium formulation containing 23% HCl (toilet bowl cleaner), and sodium hypochlorite (greater than 5,000 ppm [greater than 5,000 micrograms/ml] of free chlorine) reduced the virus titer by greater than 99.9%; phenolics, iodine-based products, alcohols, and solutions of acetic, peracetic, citric, and phosphoric acids were unable to do so.
摘要
在受污染的不锈钢圆盘上评估甲型肝炎病毒的消毒效果。将10微升粪便悬液中的甲型肝炎病毒滴在每个圆盘的中心，干燥20分钟，然后覆盖20微升测试产品1分钟。在测试的20种制剂中，只有2%的戊二醛、含23%盐酸的季铵制剂（马桶清洁剂）和次氯酸钠（游离氯大于5000 ppm [大于5000微克/毫升]）能使病毒滴度降低99.9%以上；酚类、碘基产品、酒精以及乙酸、过乙酸、柠檬酸和磷酸溶液均无法做到这一点。
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