Department of Cariology, Restorative Sciences and Endodontics, University of Michigan School of Dentistry, Ann Arbor, MI 48109, USA.
J Dent Res. 2011 Oct;90(10):1189-96. doi: 10.1177/0022034511413927. Epub 2011 Jul 15.
The purpose of this Institutional Review Board-approved study was to identify risk factors of caries lesion progression in children enrolled in rural schools in Puerto Rico. A convenience sample of 408 children (5-13 yrs old) was examined at baseline and at 12 and 24 mos with the International Caries Detection and Assessment System (ICDAS). A total of 395 caregivers completed a 25-item questionnaire including socio-demographic, dietary, protective factors, disease experience, and access to care. Caries progression was significant (89% and 91% at 12 and 24 mos, respectively). Multiple-variable models for predicting children with lesion progression and numbers of lesions progressing were calculated for 2 outcome variables (any-progression vs. progression-toward-cavitation). Models developed had areas under the receiver operating characteristic (ROC) curve ranging between 0.70 and 0.79 and were very similar regardless of the outcome (progression criteria), prediction time (12-24 mos), or inclusion (or not) of previous caries experience. Significant predictors of disease progression collected through a parent-completed questionnaire included questions related to caries experience in the child or caregiver, and the caregiver's rating of the child's oral health.
这项经机构审查委员会批准的研究旨在确定波多黎各农村学校儿童龋齿病变进展的风险因素。在基线和 12 个月及 24 个月时,采用国际龋齿检测和评估系统(ICDAS)对 408 名(5-13 岁)儿童进行了检查。共有 395 名照顾者完成了一份 25 项的问卷,其中包括社会人口统计学、饮食、保护因素、疾病经历和获得护理的情况。龋齿进展显著(12 个月和 24 个月时分别为 89%和 91%)。针对两个结果变量(任何进展与朝向龋洞的进展)计算了预测有病变进展儿童和病变进展数量的多变量模型。为 2 个结果变量(任何进展与朝向龋洞的进展)计算了预测有病变进展儿童和病变进展数量的多变量模型。为 2 个结果变量(任何进展与朝向龋洞的进展)计算了预测有病变进展儿童和病变进展数量的多变量模型。开发的模型的接收者操作特征(ROC)曲线下面积在 0.70 到 0.79 之间,无论结果(进展标准)、预测时间(12-24 个月)如何,或是否包括(或不包括)既往龋齿经历,都非常相似。通过家长完成的问卷收集的疾病进展的显著预测因素包括与儿童或照顾者的龋齿经历以及照顾者对儿童口腔健康的评价相关的问题。