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艰难梭菌感染酶免疫检测阴性的临床和感染控制意义。

Clinical and infection control implications of Clostridium difficile infection with negative enzyme immunoassay for toxin.

机构信息

Department of Infectious Diseases, University Hospitals of Cleveland, OH, USA.

出版信息

Clin Infect Dis. 2011 Aug 1;53(3):287-90. doi: 10.1093/cid/cir361.

DOI:10.1093/cid/cir361
PMID:21765078
Abstract

In a prospective study of 132 patients with a diagnosis of Clostridium difficile infection (CDI) by polymerase chain reaction, 43 (32%) had enzyme immunoassay (EIA) results negative for toxin. EIA-negative patients with CDI did not differ in clinical presentation from EIA-positive patients and presented a similar risk for transmission of spores.

摘要

在一项针对 132 例经聚合酶链反应诊断为艰难梭菌感染 (CDI) 的患者的前瞻性研究中，43 例 (32%) 的酶联免疫吸附试验 (EIA) 结果为毒素阴性。EIA 阴性的 CDI 患者在临床表现上与 EIA 阳性患者没有差异，且具有相似的孢子传播风险。

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