PGAT：微生物基因组的多菌株分析资源。
PGAT: a multistrain analysis resource for microbial genomes.
机构信息
Department of Microbiology, University of Washington, Seattle, WA 98195, USA.
出版信息
Bioinformatics. 2011 Sep 1;27(17):2429-30. doi: 10.1093/bioinformatics/btr418. Epub 2011 Jul 15.
Abstract
MOTIVATION
The Prokaryotic-genome Analysis Tool (PGAT) is a web-based database application for comparing gene content and sequence across multiple microbial genomes facilitating the discovery of genetic differences that may explain observed phenotypes. PGAT supports database queries to identify genes that are present or absent in user-selected genomes, comparison of sequence polymorphisms in sets of orthologous genes, multigenome display of regions surrounding a query gene, comparison of the distribution of genes in metabolic pathways and manual community annotation.
AVAILABILITY AND IMPLEMENTATION
The PGAT website may be accessed at http://nwrce.org/pgat.
CONTACT
摘要
动机
原核生物基因组分析工具（PGAT）是一个基于网络的数据库应用程序，用于比较多个微生物基因组中的基因内容和序列，有助于发现可能解释观察到的表型差异的遗传差异。PGAT 支持数据库查询，以确定用户选择的基因组中存在或不存在的基因，比较一组同源基因中的序列多态性，围绕查询基因的多基因组显示区域，比较代谢途径中基因的分布以及手动社区注释。
可用性和实现
PGAT 网站可在 http://nwrce.org/pgat 访问。
联系人
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