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Multi-Physics MRI-Based Two-Layer Fluid-Structure Interaction Anisotropic Models of Human Right and Left Ventricles with Different Patch Materials: Cardiac Function Assessment and Mechanical Stress Analysis.基于多物理场磁共振成像的具有不同贴片材料的人体左右心室两层流固相互作用各向异性模型:心功能评估与机械应力分析
Comput Struct. 2011 Jun;89(11-12):1059-1068. doi: 10.1016/j.compstruc.2010.12.012.
2
Effect of Patch Mechanical Properties on Right Ventricle Function Using MRI-Based Two-Layer Anisotropic Models of Human Right and Left Ventricles.使用基于MRI的人体右心室和左心室两层各向异性模型研究补片力学性能对右心室功能的影响。
Comput Model Eng Sci. 2010;56(2):113-130.
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Two-layer passive/active anisotropic FSI models with fiber orientation: MRI-based patient-specific modeling of right ventricular response to pulmonary valve insertion surgery.具有纤维取向的两层被动/主动各向异性流固耦合模型:基于MRI的肺动脉瓣植入手术右心室反应的患者特异性建模。
Mol Cell Biomech. 2007 Sep;4(3):159-76.
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Patient-specific MRI-based 3D FSI RV/LV/patch models for pulmonary valve replacement surgery and patch optimization.基于患者特异性MRI的三维流体结构相互作用右心室/左心室/补片模型用于肺动脉瓣置换手术及补片优化。
J Biomech Eng. 2008 Aug;130(4):041010. doi: 10.1115/1.2913339.
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In vivo MRI-Based 3D FSI RV/LV Models for Human Right Ventricle and Patch Design for Potential Computer-Aided Surgery Optimization.基于体内磁共振成像的用于人类右心室的三维流体结构相互作用右心室/左心室模型及用于潜在计算机辅助手术优化的补片设计
Comput Struct. 2007;85(11-14):988-997. doi: 10.1016/j.compstruc.2006.11.008.
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Image-Based Patient-Specific Ventricle Models with Fluid-Structure Interaction for Cardiac Function Assessment and Surgical Design Optimization.基于图像的特定患者心室模型,具有用于心功能评估和手术设计优化的流固耦合作用
Prog Pediatr Cardiol. 2010 Dec 1;30(1-2):51-62. doi: 10.1016/j.ppedcard.2010.09.007.
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Using contracting band to improve right ventricle ejection fraction for patients with repaired tetralogy of Fallot: a modeling study using patient-specific CMR-based 2-layer anisotropic models of human right and left ventricles.采用收缩带提高法洛四联症修复术后患者右心室射血分数:基于患者特定的心脏磁共振成像的 2 层各向异性模型的建模研究。
J Thorac Cardiovasc Surg. 2013 Jan;145(1):285-93, 293.e1-2. doi: 10.1016/j.jtcvs.2012.03.009. Epub 2012 Apr 7.
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Multi-Band Surgery for Repaired Tetralogy of Fallot Patients With Reduced Right Ventricle Ejection Fraction: A Pilot Study.右心室射血分数降低的法洛四联症修复患者的多频段手术:一项初步研究。
Front Physiol. 2020 Mar 19;11:198. doi: 10.3389/fphys.2020.00198. eCollection 2020.
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Patient-Specific MRI-Based Right Ventricle Models Using Different Zero-Load Diastole and Systole Geometries for Better Cardiac Stress and Strain Calculations and Pulmonary Valve Replacement Surgical Outcome Predictions.基于患者特异性MRI的右心室模型,使用不同的零负荷舒张期和收缩期几何形状,以更好地进行心脏应力和应变计算以及肺动脉瓣置换手术结果预测。
PLoS One. 2016 Sep 14;11(9):e0162986. doi: 10.1371/journal.pone.0162986. eCollection 2016.

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3
Numerical Simulation Study on the Mechanism of Formation of Apical Aneurysm in Hypertrophic Cardiomyopathy With Midventricular Obstruction.肥厚型心肌病伴心室中部梗阻时心尖部动脉瘤形成机制的数值模拟研究
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4
Patient-specific in vivo right ventricle material parameter estimation for patients with tetralogy of Fallot using MRI-based models with different zero-load diastole and systole morphologies.基于 MRI 的不同零负荷舒张和收缩形态模型对法洛四联症患者进行特定于患者的右心室材料参数估计。
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Comparison of Right Ventricle Morphological and Mechanical Characteristics for Healthy and Patients with Tetralogy of Fallot: An In Vivo MRI-Based Modeling Study.健康人与法洛四联症患者右心室形态学和力学特征的比较:一项基于体内磁共振成像的建模研究。
Mol Cell Biomech. 2017;14(3):137-151. doi: 10.3970/mcb.2017.014.137.
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Patient-specific CT-based 3D passive FSI model for left ventricle in hypertrophic obstructive cardiomyopathy.基于患者特异性CT的肥厚型梗阻性心肌病左心室三维被动流固耦合模型
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Patient-Specific MRI-Based Right Ventricle Models Using Different Zero-Load Diastole and Systole Geometries for Better Cardiac Stress and Strain Calculations and Pulmonary Valve Replacement Surgical Outcome Predictions.基于患者特异性MRI的右心室模型,使用不同的零负荷舒张期和收缩期几何形状,以更好地进行心脏应力和应变计算以及肺动脉瓣置换手术结果预测。
PLoS One. 2016 Sep 14;11(9):e0162986. doi: 10.1371/journal.pone.0162986. eCollection 2016.
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Interface Focus. 2016 Apr 6;6(2):20150083. doi: 10.1098/rsfs.2015.0083.

本文引用的文献

1
First finite element model of the left ventricle with mitral valve: insights into ischemic mitral regurgitation.左心室与二尖瓣的首个有限元模型:对缺血性二尖瓣反流的深入了解。
Ann Thorac Surg. 2010 May;89(5):1546-53. doi: 10.1016/j.athoracsur.2010.02.036.
2
In vivo MRI-Based 3D FSI RV/LV Models for Human Right Ventricle and Patch Design for Potential Computer-Aided Surgery Optimization.基于体内磁共振成像的用于人类右心室的三维流体结构相互作用右心室/左心室模型及用于潜在计算机辅助手术优化的补片设计
Comput Struct. 2007;85(11-14):988-997. doi: 10.1016/j.compstruc.2006.11.008.
3
Effects of regional dysfunction and late gadolinium enhancement on global right ventricular function and exercise capacity in patients with repaired tetralogy of Fallot.法洛四联症修复术后患者局部功能障碍和延迟钆增强对整体右心室功能及运动能力的影响
Circulation. 2009 Mar 17;119(10):1370-7. doi: 10.1161/CIRCULATIONAHA.108.816546. Epub 2009 Mar 2.
4
Increased myocyte content and mechanical function within a tissue-engineered myocardial patch following implantation.植入后组织工程心肌补片中的心肌细胞含量增加及机械功能增强。
Tissue Eng Part A. 2009 Aug;15(8):2189-201. doi: 10.1089/ten.tea.2008.0430.
5
Changes in wall motion and blood flow in the outflow tract of chick embryonic hearts observed with optical coherence tomography after outflow tract banding and vitelline-vein ligation.在进行流出道结扎和卵黄静脉结扎后,用光学相干断层扫描观察鸡胚心脏流出道壁运动和血流的变化。
Phys Med Biol. 2008 Sep 21;53(18):5077-91. doi: 10.1088/0031-9155/53/18/015. Epub 2008 Aug 22.
6
Patient-specific MRI-based 3D FSI RV/LV/patch models for pulmonary valve replacement surgery and patch optimization.基于患者特异性MRI的三维流体结构相互作用右心室/左心室/补片模型用于肺动脉瓣置换手术及补片优化。
J Biomech Eng. 2008 Aug;130(4):041010. doi: 10.1115/1.2913339.
7
Subject-specific computational simulation of left ventricular flow based on magnetic resonance imaging.基于磁共振成像的左心室血流特定对象计算模拟
Proc Inst Mech Eng H. 2008 May;222(4):475-85. doi: 10.1243/09544119JEIM310.
8
Two-layer passive/active anisotropic FSI models with fiber orientation: MRI-based patient-specific modeling of right ventricular response to pulmonary valve insertion surgery.具有纤维取向的两层被动/主动各向异性流固耦合模型:基于MRI的肺动脉瓣植入手术右心室反应的患者特异性建模。
Mol Cell Biomech. 2007 Sep;4(3):159-76.
9
Systolic modeling of the left ventricle as a mechatronic system: determination of myocardial fiber's sarcomere contractile characteristics and new performance indices.将左心室作为机电一体化系统的收缩期建模:心肌纤维肌节收缩特性的测定及新的性能指标
Mol Cell Biomech. 2005 Dec;2(4):217-33.
10
Surgical management of right ventricular dysfunction late after repair of tetralogy of fallot: right ventricular remodeling surgery.法洛四联症修复术后晚期右心室功能障碍的外科治疗:右心室重塑手术
Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2006:29-34. doi: 10.1053/j.pcsu.2006.02.007.

基于多物理场磁共振成像的具有不同贴片材料的人体左右心室两层流固相互作用各向异性模型:心功能评估与机械应力分析

Multi-Physics MRI-Based Two-Layer Fluid-Structure Interaction Anisotropic Models of Human Right and Left Ventricles with Different Patch Materials: Cardiac Function Assessment and Mechanical Stress Analysis.

作者信息

Tang Dalin, Yang Chun, Geva Tal, Gaudette Glenn, Del Nido Pedro J

机构信息

Mathematical Sciences Department, Worcester Polytechnic Institute, Worcester, MA 01609.

出版信息

Comput Struct. 2011 Jun;89(11-12):1059-1068. doi: 10.1016/j.compstruc.2010.12.012.

DOI:10.1016/j.compstruc.2010.12.012
PMID:21765559
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3134331/
Abstract

Multi-physics right and left ventricle (RV/LV) fluid-structure interaction (FSI) models were introduced to perform mechanical stress analysis and evaluate the effect of patch materials on RV function. The FSI models included three different patch materials (Dacron scaffold, treated pericardium, and contracting myocardium), two-layer construction, fiber orientation, and active anisotropic material properties. The models were constructed based on cardiac magnetic resonance (CMR) images acquired from a patient with severe RV dilatation and solved by ADINA. Our results indicate that the patch model with contracting myocardium leads to decreased stress level in the patch area, improved RV function and patch area contractility.

摘要

引入多物理场左右心室(RV/LV)流固耦合(FSI)模型来进行机械应力分析,并评估补片材料对右心室功能的影响。这些FSI模型包括三种不同的补片材料(涤纶支架、处理过的心包和收缩期心肌)、双层结构、纤维取向和活性各向异性材料特性。这些模型基于从一名严重右心室扩张患者获取的心脏磁共振(CMR)图像构建,并由ADINA求解。我们的结果表明,具有收缩期心肌的补片模型可导致补片区域的应力水平降低、右心室功能改善以及补片区域收缩性增强。