异基因造血细胞移植后 BK 病毒相关性肾病的评估和管理。
Evaluation and management of BK virus-associated nephropathy following allogeneic hematopoietic cell transplantation.
机构信息
Department of Internal Medicine, University of North Dakota, ND, USA.
出版信息
Biol Blood Marrow Transplant. 2011 Nov;17(11):1589-93. doi: 10.1016/j.bbmt.2011.07.010. Epub 2011 Jul 20.
Abstract
BK virus nephropathy is a common cause of graft loss in kidney transplant recipients. Cases of BK nephropathy following allogeneic hematopoietic cell transplantation (HCT) are underreported. An increased incidence of BK virus-associated nephropathy is being seen in the setting of more profound and prolonged immunosuppression following solid organ transplantation and HCT. We will review diagnostic and treatment modalities for BK-associated nephropathy following allogeneic HCT.
摘要
BK 病毒肾病是肾移植受者移植物丢失的常见原因。异基因造血细胞移植 (HCT) 后发生 BK 肾病的病例报道较少。在实体器官移植和 HCT 后更深度和更长期的免疫抑制背景下，BK 病毒相关性肾病的发生率增加。我们将回顾异基因 HCT 后 BK 相关肾病的诊断和治疗方法。
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