癌症患者急性肾损伤的诊断与治疗新进展。

Recent advances in diagnosis and treatment of acute kidney injury in patients with cancer.

机构信息

Renal Division, Brigham and Women's Hospital, United States.

出版信息

Eur J Intern Med. 2011 Aug;22(4):348-54. doi: 10.1016/j.ejim.2011.02.002. Epub 2011 Mar 21.

DOI:10.1016/j.ejim.2011.02.002

Abstract

Acute Kidney Injury (AKI) is a common complication in patients with cancer and even though there are many causes of renal failure in this population the classical classification of prerenal, renal, and postrenal is useful as a diagnostic guide. Important risk factors for AKI are dehydration, use of nephrotoxic drugs, preexisting renal impairment and large tumor burden. The development of AKI is associated with poor prognosis but early recognition and treatment initiation are associated with better outcomes in this population.

摘要

急性肾损伤（AKI）是癌症患者的常见并发症，尽管该人群中导致肾衰竭的原因很多，但作为诊断指南，传统的肾前性、肾性和肾后性分类仍然很有用。AKI 的重要危险因素包括脱水、使用肾毒性药物、原有肾功能不全和大肿瘤负荷。AKI 的发生与预后不良有关，但在该人群中，早期识别和治疗开始与更好的结局相关。