瘙痒与肾衰竭。
Pruritus and renal failure.
作者信息
Berger Timothy G, Steinhoff Martin
机构信息
Department of Dermatology, University of California San Francisco, San Francisco, CA 94143, USA.
出版信息
Semin Cutan Med Surg. 2011 Jun;30(2):99-100. doi: 10.1016/j.sder.2011.04.005.
Abstract
Patients with renal failure, usually end-stage renal disease (ESRD), commonly are afflicted by severe pruritus. The pathogenesis of ESRD pruritus is unknown, but improving the quality of dialysis can reduce the prevalence and severity of ESRD pruritus. Topical and systemic agents as well as broadband ultraviolet phototherapy can be extremely beneficial. Gabapentin has been recently discovered as an effective agent for the patient with ESRD pruritus. Kappa opiate agonists are promising new therapeutic options.
摘要
肾衰竭患者，通常是终末期肾病（ESRD）患者，常受严重瘙痒困扰。ESRD瘙痒的发病机制尚不清楚，但改善透析质量可降低ESRD瘙痒的发生率和严重程度。局部和全身用药以及宽带紫外线光疗可能极为有益。加巴喷丁最近被发现是治疗ESRD瘙痒患者的有效药物。κ阿片受体激动剂是很有前景的新治疗选择。
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