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双相 I 障碍患者在躁狂、混合和抑郁发作期间的创造力和执行功能。

Creativity and executive function across manic, mixed and depressive episodes in bipolar I disorder.

机构信息

Mood Disorders Unit (GRUDA), Department and Institute of Psychiatry, School of Medicine, University of Sao Paulo (IPq HC-FMUSP), Brazil.

出版信息

J Affect Disord. 2011 Dec;135(1-3):292-7. doi: 10.1016/j.jad.2011.06.024. Epub 2011 Jul 21.

Abstract

INTRODUCTION

Creativity is a complex construct involving affective and cognitive components. Bipolar Disorder (BD) has been associated with creativity and is characterized by a wide range of affective and cognitive symptoms. Although studies of creativity in BD have tended to focus on creativity as a trait variable in medicated euthymic patients, it probably fluctuates during symptomatic states of BD. Since creativity is known to involve key affective and cognitive components, it is plausible to speculate that cognitive deficits and symptoms present in symptomatic BD could interfere with creativity.

MATERIAL AND METHODS

Sixty-seven BD type I patients medication free, age 18-35 years and experiencing a maniac, mixed, or depressive episodes, were assessed for creativity, executive functioning, and intelligence.

RESULTS

Manic and mixed state patients had higher creativity scores than depressive individuals. Creativity was influenced by executive function measures only in manic patients. Intelligence did not influence creativity for any of the mood episode types.

CONCLUSION

We propose that creativity in BD might be linked to the putative hyperdopaminergic state of mania and be dependent on intact executive function. Future studies should further explore the role of dopaminergic mechanisms in creativity in BD.

摘要

简介

创造力是一种涉及情感和认知成分的复杂结构。双相情感障碍(BD)与创造力有关,其特征是广泛的情感和认知症状。尽管 BD 中的创造力研究倾向于关注药物治疗的心境稳定患者的特质变量,但它可能在 BD 的症状状态期间波动。由于创造力已知涉及关键的情感和认知成分,因此可以推测 BD 中的认知缺陷和症状可能会干扰创造力。

材料和方法

67 名 18-35 岁的 BD 型 I 患者(无药物治疗),经历过躁狂、混合或抑郁发作,接受了创造力、执行功能和智力评估。

结果

躁狂和混合状态患者的创造力得分高于抑郁个体。只有在躁狂患者中,创造力才会受到执行功能测量的影响。对于任何一种情绪发作类型,智力都不会影响创造力。

结论

我们提出,BD 中的创造力可能与躁狂症的假定高多巴胺能状态有关,并且依赖于完整的执行功能。未来的研究应进一步探索多巴胺能机制在 BD 中的创造力中的作用。

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