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食管癌:伊朗北部里海东南部地区的5年生存率

Esophageal cancer: 5-year survival rate at south-east of Caspian sea of northern Iran.

作者信息

Taziki Mohammad Hussin, Rajaee Siamak, Behnampour Naser, Tadrisee Massoud, Mansourian Azad Reza

机构信息

Department of Biochemistry and Biophysic, Gorgan Medical School, Gorgan, India.

出版信息

J Cancer Res Ther. 2011 Apr-Jun;7(2):135-7. doi: 10.4103/0973-1482.82923.

Abstract

BACKGROUND

Locating at southern margin of Caspian sea and Asian esophagus cancer cordon Golestan state is one of the most common sites of this cancer.

OBJECTIVE

This study designed to evaluate the 5-years survival rate of esophagus cancer.

MATERIALS AND METHODS

55 patients with esophagus cancer diagnosed by pathologic examination, age, gender, type of tumor, clinical manifestation on the time of tumor metastases, treatment and patient survival time studied. The collecting data were analyzed by SPSS 11.5, and life table and Kaplan Meier methods were applied.

RESULTS

55 patients studied included 11 females and 44 males respectively with average survival life time of 12.8 months for the 5-year survival rate for patients diagnosed at early stage was 0.025, patients with systemic symptoms such as weight loss was 0.00. Far metastases adverse effect on highest survivals was observed among patients who underwent surgery; the survival rate for such patients was about 0.014.

CONCLUSIONS

Esophageal cancer is high in southern margin of Caspian Sea, it is suggested to design studies to find the probable risk factors and the screening tests for on-time diagnosis.

摘要

背景

位于里海南岸且处于亚洲食管癌高发地带的戈勒斯坦省是这种癌症最常见的发病地区之一。

目的

本研究旨在评估食管癌的5年生存率。

材料与方法

对55例经病理检查确诊的食管癌患者的年龄、性别、肿瘤类型、肿瘤转移时的临床表现、治疗情况及患者生存时间进行研究。收集的数据采用SPSS 11.5进行分析,并应用寿命表法和Kaplan Meier法。

结果

所研究的55例患者中,女性11例,男性44例,平均生存时间为12.8个月。早期诊断患者的5年生存率为0.025,有体重减轻等全身症状的患者生存率为0.00。在接受手术的患者中,远处转移对最高生存率有不良影响;此类患者的生存率约为0.014。

结论

里海南岸食管癌发病率较高,建议开展研究以找出可能的危险因素及用于早期诊断的筛查试验。

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