Department of Mechanical and Mechatronics Engineering, University of Waterloo, Waterloo, Ontario, Canada N2L 3G1.
Lab Chip. 2011 Sep 7;11(17):2929-40. doi: 10.1039/c1lc20229d. Epub 2011 Jul 18.
A new micro-valve using the electrokinetic motion of a Janus particle is introduced in this paper. A Janus particle with a conducting hemisphere and a non-conducting hemisphere is placed in a junction of several microchannels. Under an applied electric field, the induced-charge electrokinetic flow around the conducting side of the Janus particle forms vortices. The vortices push the particle moving forwards to block the entrance of a microchannel. By switching the direction of the applied electric field, the motion of the Janus particle can be changed to block different microchannels. This paper develops a theoretical model and conducts numerical simulations of the three-dimensional transient motion of the Janus particle. The results show that this Janus particle-based micro-valve is feasible for switching and controlling the flow rate in a microfluidic chip. This method is simple in comparison with other types of micro-valve methods. It is easy for fabrication, for operation control, and has a fast response time. To better understand the micro-valve functions, comparisons with a non-conducting particle and a fully conducting particle were made. Results proved that only a Janus particle can fulfill the requirements of such a micro-valve.
本文介绍了一种利用 Janus 粒子的电动运动的新型微阀。将具有导电半球和非导电半球的 Janus 粒子放置在几个微通道的交界处。在施加电场的情况下,Janus 粒子导电侧周围感应电荷的电泳流形成涡旋。这些涡旋推动粒子向前移动以阻塞微通道的入口。通过切换施加电场的方向,可以改变 Janus 粒子的运动来阻塞不同的微通道。本文建立了 Janus 粒子的三维瞬态运动的理论模型并进行了数值模拟。结果表明,这种基于 Janus 粒子的微阀可用于切换和控制微流控芯片中的流量。与其他类型的微阀方法相比,该方法简单。制造、操作控制都很容易,并且响应时间很快。为了更好地理解微阀的功能,与非导电粒子和完全导电粒子进行了比较。结果表明,只有 Janus 粒子才能满足这种微阀的要求。