Centre for Medical Entomology and Vector Management, National Centre for Diseases Control, 22-Shamnath Marg, Delhi 110054, India.
Asian Pac J Trop Med. 2011 Jun;4(6):426-9. doi: 10.1016/S1995-7645(11)60119-3.
To understand the insecticide resistance status of Culex quinquefasciatus Say (Diptera: Culicidae) (Cx. Quinquefasciatus) to deltamethrin, cyfluthrin, permethrin, lambdacyhalothrin, DDT and malathion in filarial endemic areas of Uttar Pradesh, India.
Insecticide susceptibility assays were performed on wild-caught adult female Cx. quinquefasciatus mosquitoes to deltamethrin (0.05%), cyfluthrin (0.15%), permethrin (0.75%), lambdacyhalothrin (0.05%), malathion (5.0%) and DDT (4.0%), the discriminating doses recommended by the World Health Organisation (WHO).
The data showed that Cx. quinquefasciatus is highly resistant to DDT and malathion; the mortality was 28.33% and 27.5%, respectively and incipient resistance to synthetic pyrethroids (deltamethrin, cyfluthrin, permethrin, and lambdacyhalothrin), where mortality ranged from 95.83% in permethrin to 98.33% in cyfluthrin and lambdacyhalothrin. Knockdown times (KDT(50)) in response to synthetic pyrethroids varied significantly between different insecticides (P<0.01) from 31.480 min for permethrin to 21.650 for cyfluthrin.
The results presents here provide the status report of the insecticide resistance/susceptibility of Cx. quinquefasciatus in major filaria endemic areas of northern India.
了解印度北方邦丝虫病流行地区致倦库蚊对溴氰菊酯、氯氟氰菊酯、氯菊酯、高效氯氟氰菊酯、滴滴涕和马拉硫磷的抗药性状况。
对野外捕获的成年雌性致倦库蚊进行溴氰菊酯（0.05%）、氯氟氰菊酯（0.15%）、氯菊酯（0.75%）、高效氯氟氰菊酯（0.05%）、马拉硫磷（5.0%）和滴滴涕（4.0%）的杀虫剂敏感性测定，这些剂量是世界卫生组织（WHO）推荐的鉴别剂量。
数据显示，致倦库蚊对滴滴涕和马拉硫磷高度耐药；死亡率分别为 28.33%和 27.5%，对合成拟除虫菊酯（溴氰菊酯、氯氟氰菊酯、氯菊酯和高效氯氟氰菊酯）也有初步抗性，死亡率范围从氯菊酯的 95.83%到氯氟氰菊酯和高效氯氟氰菊酯的 98.33%。对合成拟除虫菊酯的击倒时间（KDT（50））在不同杀虫剂之间差异显著（P<0.01），从氯菊酯的 31.480 分钟到氯氟氰菊酯的 21.650 分钟。
这里提供的结果报告了印度北方邦主要丝虫病流行地区致倦库蚊对杀虫剂的抗药性/敏感性状况。
