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一个正在消失的遗产:精神分裂症的临床核心。

A disappearing heritage: the clinical core of schizophrenia.

机构信息

Psychiatric Center Hvidovre , University of Copenhagen, Copenhagen, Denmark.

出版信息

Schizophr Bull. 2011 Nov;37(6):1121-30. doi: 10.1093/schbul/sbr081. Epub 2011 Jul 19.

Abstract

This article traces the fundamental descriptive features of schizophrenia described in the European continental literature form Kraepelin and Bleuler, culminating with the creation of the International Classification of Diseases (ICD)-8 (1974). There was a consensus among the researchers that the specificity and typicality of schizophrenia was anchored to its "fundamental" clinical core (with trait status) and not to positive psychotic features, which were considered as "state", "accessory" phenomena. The clinical core of schizophrenia was, in a diluted form, constitutive of the spectrum conditions ("schizoidia" and "latent schizophrenia"). The fundamental features are manifest across all domains of consciousness: subjective experience, expression, cognition, affectivity, behavior, and willing. Yet, the specificity of the core was only graspable at a more comprehensive Gestalt-level, variously designated (eg, discordance, autism, "Spaltung"), and not on the level of single features. In other words, the phenomenological specificity was seen as being expressive of a fundamental structural or formal change of the patient's mentality (consciousness, subjectivity). This overall change transpires through the single symptoms and signs, lending them a characteristic phenomenological pattern. This concept of schizophrenia bears little resemblance to the current operational definitions. The Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, and ICD-10 seem to diagnose a subset of patients with chronic paranoid-hallucinatory variant of schizophrenia.

摘要

本文追溯了从克雷丕林和布洛伊勒时代的欧洲大陆文献中描述的精神分裂症的基本描述特征,最终形成了《国际疾病分类》(ICD-8,1974 年)。研究人员达成共识,认为精神分裂症的特异性和典型性是基于其“基本”临床核心(特征状态),而不是阳性精神病特征,后者被认为是“状态”、“附加”现象。精神分裂症的临床核心以稀释的形式构成了谱系条件(“分裂样”和“潜伏性精神分裂症”)。基本特征在所有意识领域都表现出来:主观体验、表达、认知、情感、行为和意愿。然而,核心的特异性只能在更全面的格式塔层面上把握,其各种指定的术语(例如,不和谐、自闭症、“分裂”),而不是单个特征的层面。换句话说,现象学特异性被视为表达患者心理(意识、主观性)的一种基本结构或形式变化。这种精神分裂症的概念与当前的操作定义几乎没有相似之处。《精神障碍诊断与统计手册》(DSM-IV)和《国际疾病分类》第 10 版似乎诊断出了一组慢性妄想幻觉变异型精神分裂症患者。

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A disappearing heritage: the clinical core of schizophrenia.一个正在消失的遗产:精神分裂症的临床核心。
Schizophr Bull. 2011 Nov;37(6):1121-30. doi: 10.1093/schbul/sbr081. Epub 2011 Jul 19.

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