Niafar Mitra, Bahrami Amir, Aliasgharzadeh Akbar, Aghamohammadzadeh Naser, Najafipour Farzad, Mobasseri Majid
Endocrinology and Metabolism Section, Department of Medicine, Imam Reza Hospital, Tabriz, Iran.
J Res Med Sci. 2009 May;14(3):171-7.
There are few epidemiologic studies on vitamin D status of postmenopausal women in the Middle East countries. This study aimed to investigate the 25-hydroxyvitamin D levels in postmenopausal women living in the north-west of Iran.
Using the records of the local household registry, 300 cases were enrolled by simple random sampling. Serum 25-hydroxyvitamin D levels were determined by fully automated chemiluminescent immunoassay. In addition, the study included survey questions regarding age, body weight and height, use of supplements and skin protection agents and clinical and reproductive histories.
Our cases had the mean age of 63.41 ± 4.64 years with menopause duration of 16.79 ± 6.15 years. Median and interquartile 25-75 range of vitamin D were 14.20 ng/ml and 7-37.2 ng/ml respectively. We found hypovitaminosis D [25(OH) D < 10 ng/ml] in 38.3% of our cases. Serum 25(OH) D concentrations were not significantly correlated with age or BMI.
These findings indicate that 25(OH) D levels in postmenopausal women of north-west Iran are low. Studies to elucidate and assess the dietary intake of vitamin D in elderly women of this region can be of further benefit.
中东国家关于绝经后女性维生素D状况的流行病学研究较少。本研究旨在调查居住在伊朗西北部的绝经后女性的25-羟基维生素D水平。
利用当地家庭登记记录，通过简单随机抽样纳入300例病例。采用全自动化学发光免疫分析法测定血清25-羟基维生素D水平。此外，该研究还包括有关年龄、体重和身高、补充剂和皮肤保护剂的使用以及临床和生殖史的调查问卷。
我们的病例平均年龄为63.41±4.64岁，绝经持续时间为16.79±6.15年。维生素D的中位数和四分位数间距25-75范围分别为14.20 ng/ml和7-37.2 ng/ml。我们发现38.3%的病例存在维生素D缺乏症[25(OH)D<10 ng/ml]。血清25(OH)D浓度与年龄或BMI无显著相关性。
这些发现表明，伊朗西北部绝经后女性的25(OH)D水平较低。开展研究以阐明和评估该地区老年女性的维生素D膳食摄入量可能会带来更多益处。
