Petzke Klaus J, Lemke Susen, Klaus Susanne
Group of Stable Isotopes and of Energy Metabolism, German Institute of Human Nutrition in Potsdam-Rehbruecke (DIfE), Arthur-Scheunert-Allee 114-116, 14558 Nuthetal, Germany.
J Nutr Metab. 2011;2011:210930. doi: 10.1155/2011/210930. Epub 2011 Jun 14.
Aims. To investigate whether changes of meat consumption can affect body composition and laboratory parameters in healthy, normal weight, young women without the aim to reduce body weight. Research Design and Methods. Women volunteered to eat low-fat meat in addition to their habitual diet (M) or to exclude meat products from their diet (NOM). After 4 weeks M and NOM were crossed over between subjects. Changes in nutrient intake, morphometrics and plasma parameters were compared during M and NOM. Results. Daily protein intake (means ± SD) was 2.25 ± 0.35 (25.2% of energy) and 1.15 ± 0.26 g/kg (14.0% of energy) during M and NOM, respectively. Fat-free body mass (FFM) increased during M (0.7 ± 1.0 kg, P = .02) and decreased during NOM (-0.8 ± 0.8 kg, P = .003). Body fat mass was unchanged. Concentrations of total cholesterol (-7%), LDL-cholesterol (-8%), and glucose (-4%) deceased significantly after M. Fasting glutamine concentrations were decreased by M and increased by NOM. Conclusions. Additional meat intake can increase FFM without adverse effects on blood lipid concentrations. Long-term studies are required. Urinary excretion of 3-methylhistidine could represent a biomarker for meat protein consumption.
目的。调查在不旨在减轻体重的健康、体重正常的年轻女性中，肉类摄入量的变化是否会影响身体成分和实验室参数。研究设计与方法。女性志愿者在其日常饮食基础上额外食用低脂肉类（M组）或从饮食中排除肉类产品（非肉类组，NOM）。4周后M组和NOM组在受试者之间交叉。比较M组和NOM组期间营养摄入、形态测量学和血浆参数的变化。结果。M组和NOM组期间每日蛋白质摄入量（均值±标准差）分别为2.25±0.35（占能量的25.2%）和1.15±0.26克/千克（占能量的14.0%）。M组期间无脂肪体重（FFM）增加（0.7±1.0千克，P = 0.02），NOM组期间减少（-0.8±0.8千克，P = 0.003）。体脂肪量无变化。M组后总胆固醇（-7%）、低密度脂蛋白胆固醇（-8%）和葡萄糖（-4%）浓度显著下降。M组使空腹谷氨酰胺浓度降低，NOM组使其升高。结论。额外摄入肉类可增加无脂肪体重，且对血脂浓度无不良影响。需要进行长期研究。3-甲基组氨酸的尿排泄量可能代表肉类蛋白质摄入量的生物标志物。
