Program for Infection Prevention and Healthcare Epidemiology, Division of Infectious Diseases and International Health, Department of Medicine, Duke University Medical Center, Erwin Road, Durham, NC, 27710, USA,
Curr Infect Dis Rep. 2011 Oct;13(5):442-50. doi: 10.1007/s11908-011-0198-4.
Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) was a rare phenomenon until the past decade; now CA-MRSA is endemic in many communities and is the most common cause of skin and soft tissue infections presenting to emergency rooms. CA-MRSA is distinct from its hospital-acquired counterpart, and has caused devastating infections in many healthy individuals. The epidemiology of CA-MRSA continues to evolve, and the challenge is to use the most appropriate and effective therapeutic and preventative strategies against this pathogen. This article reviews the current epidemiology of CA-MRSA, its definitions, and common clinical manifestations in the community. The article also summarizes current therapeutic options for CA-MRSA as well as strategies to reduce the transmission and the impact of CA-MRSA in both community and health care settings.
社区获得性耐甲氧西林金黄色葡萄球菌（CA-MRSA）在过去十年前是一种罕见现象；现在 CA-MRSA 在许多社区流行，是急诊科就诊的皮肤和软组织感染的最常见原因。CA-MRSA 与医院获得性耐甲氧西林金黄色葡萄球菌不同，它已在许多健康个体中引起严重感染。CA-MRSA 的流行病学仍在不断演变，挑战在于针对这种病原体使用最合适和最有效的治疗和预防策略。本文综述了 CA-MRSA 的当前流行病学、定义以及在社区中的常见临床表现。本文还总结了 CA-MRSA 的当前治疗选择以及减少社区和医疗保健环境中 CA-MRSA 传播和影响的策略。
