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美国西班牙裔人群中 HIV/AIDS 生存状况和延迟诊断的系统评价

A systematic review of HIV/AIDS survival and delayed diagnosis among Hispanics in the United States.

机构信息

Department of Internal Medicine, Section of Infectious Diseases, Yale University, New Haven, CT 06517, USA.

出版信息

J Immigr Minor Health. 2012 Feb;14(1):65-81. doi: 10.1007/s10903-011-9497-y.

Abstract

HIV/AIDS disproportionately affects Hispanics. Our objective was to determine the risk of late diagnosis and rate of survival after HIV/AIDS diagnosis among Hispanics compared to other racial/ethnic groups. We performed a systematic review of the PubMed database for peer-reviewed articles published between January 2000 and September 2010. Primary outcomes included survival after HIV/AIDS diagnosis and delayed diagnoses. The definition of delayed diagnosis varied by study, ranging from concurrent HIV/AIDS diagnosis to diagnosis of AIDS within 3 years of HIV diagnosis. We found that Hispanics are at significantly greater risk for delayed diagnosis than non-Hispanic whites. Hispanic males and foreign-born Hispanics had the highest risk of late diagnosis. Available data on survival were heterogeneous, with better outcomes in some Hispanic subgroups than in others. Survival after antiretroviral initiation was similar between Hispanics and Whites. These findings emphasize the need for culturally-sensitive strategies to promote timely diagnosis of HIV infection among Hispanics and to examine the health outcomes and needs of high risk Hispanic subgroups.

摘要

艾滋病毒/艾滋病在西班牙裔人群中不成比例地高发。我们的目的是确定与其他种族/族裔群体相比,西班牙裔人群在艾滋病毒/艾滋病诊断后的晚期诊断风险和生存率。我们对 2000 年 1 月至 2010 年 9 月期间发表的同行评议的 PubMed 数据库中的文章进行了系统回顾。主要结果包括艾滋病毒/艾滋病诊断后的生存率和诊断延迟。诊断延迟的定义因研究而异,从同时诊断艾滋病毒/艾滋病到艾滋病毒诊断后 3 年内诊断出艾滋病不等。我们发现,西班牙裔人群比非西班牙裔白人人群更有可能出现诊断延迟。西班牙裔男性和外国出生的西班牙裔人群的晚期诊断风险最高。关于生存率的现有数据存在异质性,一些西班牙裔亚组的结果要好于其他亚组。抗逆转录病毒治疗开始后的生存率在西班牙裔和白人之间相似。这些发现强调需要采取文化敏感的策略,以促进西班牙裔人群中艾滋病毒感染的及时诊断,并检查高危西班牙裔亚组的健康结果和需求。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/363c/3329255/e0fa976acdab/nihms-364441-f0001.jpg

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