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包括鲜味味觉在内的味觉功能的临床测试。

Clinical test of gustatory function including umami taste.

作者信息

Mueller Christian Albert, Pintscher Karin, Renner Bertold

机构信息

Department of Otorhinolaryngology, Medical University of Vienna, Vienna, Austria.

出版信息

Ann Otol Rhinol Laryngol. 2011 Jun;120(6):358-62. doi: 10.1177/000348941112000602.

Abstract

OBJECTIVES

Assessment of gustatory function is a central part of the diagnosis of patients with chemosensory dysfunctions. The taste of monosodium glutamate was described as umami taste a century ago by Ikeda. The aim of this study was to extend a validated gustatory test with 4 concentrations of monosodium glutamate.

METHODS

The investigation included 96 subjects who reported having a normal sense of taste and smell. Taste function was assessed by 4 concentrations of sweet, sour, salty, bitter, and umami tastes (extended version) and compared to results obtained in a control group (n = 139) not presented with umami. In a subgroup of 46 participants, the complete test was repeated within 7 days to obtain retest values.

RESULTS

Group comparisons exhibited no differences in taste sensitivity for each of the 4 taste qualities (p > 0.3) and no deviation with regard to the sum of correctly identified tastants (p = 0.81). Test-retest data from the extended version revealed a high correlation of scores (r46 = 0.77; p < 0.001).

CONCLUSIONS

The results indicate that the extended version of the gustatory test is applicable for experimental and clinical settings.

摘要

目的

味觉功能评估是化学感觉功能障碍患者诊断的核心部分。一个世纪前,池田将谷氨酸钠的味道描述为鲜味。本研究的目的是扩展一项经过验证的味觉测试,使用4种浓度的谷氨酸钠。

方法

该调查纳入了96名自称味觉和嗅觉正常的受试者。通过4种浓度的甜、酸、咸、苦和鲜味(扩展版)来评估味觉功能,并与未进行鲜味测试的对照组(n = 139)的结果进行比较。在46名参与者的亚组中,在7天内重复进行完整测试以获得重测值。

结果

组间比较显示,4种味觉品质各自的味觉敏感性无差异(p > 0.3),正确识别的味觉刺激物总和也无偏差(p = 0.81)。扩展版的重测数据显示得分高度相关(r46 = 0.77;p < 0.001)。

结论

结果表明,味觉测试的扩展版适用于实验和临床环境。

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