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2005-2009 年九个国家腹主动脉瘤的治疗:一个 Vascunet 报告。

Treatment of abdominal aortic aneurysm in nine countries 2005-2009: a vascunet report.

机构信息

Department of Vascular Surgery, Guy's and St Thomas' NHS Foundation Trust, London, UK.

出版信息

Eur J Vasc Endovasc Surg. 2011 Nov;42(5):598-607. doi: 10.1016/j.ejvs.2011.06.043. Epub 2011 Jul 19.

Abstract

OBJECTIVES

To study contemporary treatment and outcome of abdominal aortic aneurysm (AAA) repair in nine countries.

DESIGN AND METHODS

Data on primary AAA repairs 2005-2009 were amalgamated from national and regional vascular registries in Australia, Denmark, Finland, Hungary, Italy, Norway, Sweden, Switzerland and the UK. Primary outcome was in-hospital or 30-day mortality. Multivariate logistic regression was used to assess case-mix.

RESULTS

31,427 intact AAA repairs were identified, mean age 72.6 years (95% CI 72.5-72.7). The rate of octogenarians and use of endovascular repair (EVAR) increased over time (p < 0.001). EVAR varied between countries from 14.7% (Finland) to 56.0% (Australia). Overall perioperative mortality after intact AAA repair was 2.8% (2.6-3.0) and was stable over time. The perioperative mortality rate varied from 1.6% (1.3-1.8) in Italy to 4.1% (2.4-7.0) in Finland. Increasing age, open repair and presence of comorbidities were associated with outcome. 7040 ruptured AAA repairs were identified, mean age 73.8 (73.6-74.0). The overall perioperative mortality was 31.6% (30.6-32.8), and decreased over time (p = 0.004).

CONCLUSIONS

The rate of AAA repair in octogenarians as well as EVAR increased over time. Perioperative outcome after intact AAA repair was stable over time, but improved after ruptured repair. Geographical differences in treatment of AAA remain.

摘要

目的

研究 9 个国家腹主动脉瘤(AAA)修复的当代治疗和结果。

方法

汇总了澳大利亚、丹麦、芬兰、匈牙利、意大利、挪威、瑞典、瑞士和英国的国家和地区血管登记处 2005-2009 年原发性 AAA 修复的数据。主要结果为住院或 30 天死亡率。采用多变量逻辑回归评估病例组合。

结果

共确定了 31427 例完整的 AAA 修复,平均年龄 72.6 岁(95%CI 72.5-72.7)。80 岁以上患者的比例和血管内修复(EVAR)的使用随着时间的推移而增加(p<0.001)。EVAR 在各国之间差异很大,从芬兰的 14.7%到澳大利亚的 56.0%。完整的 AAA 修复后围手术期死亡率为 2.8%(2.6-3.0),且随时间保持稳定。围手术期死亡率从意大利的 1.6%(1.3-1.8)到芬兰的 4.1%(2.4-7.0)不等。年龄增长、开放性修复和合并症的存在与结果相关。共确定了 7040 例破裂的 AAA 修复,平均年龄为 73.8(73.6-74.0)。整体围手术期死亡率为 31.6%(30.6-32.8),且随时间降低(p=0.004)。

结论

80 岁以上患者 AAA 修复以及 EVAR 的比例随时间增加。完整的 AAA 修复后围手术期结果随时间保持稳定,但破裂修复后有所改善。AAA 的治疗仍存在地域差异。

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