Martin E, Grütter R, Boesch C
University Children's Hospital, Ch-8032, Zürich, Switzerland.
Pediatrie. 1990;45(10):677-82.
Magnetic resonance imaging (MRI) is a noninvasive investigation technique that uses non ionizing radio waves of low quantum energy, rendering it suitable for application in children. Monitoring and anesthesia techniques allow MRL including immobilisation in a special incubator to be carried out in small infants. In vivo magnetic resonance spectroscopy (MRS) provides biochemical information on living organisms in a non-invasive manner. Such a technique has recently been used to study neonatal brain energy metabolism. High energy phosphate metabolism and phospholipid metabolism can be evaluated in this manner and available clinical correlations can be made regarding eg seizures or long term neurologic sequelae associated with a decreased phosphocreatine: orthophosphate ratio. Future trends in neonatal MRS will provide further information on morphologic and metabolic brain development.
磁共振成像（MRI）是一种非侵入性检查技术，它使用低量子能量的非电离无线电波，因此适用于儿童。监测和麻醉技术使得在小婴儿中进行MRI检查（包括固定在特殊保育箱中）成为可能。活体磁共振波谱（MRS）以非侵入性方式提供有关生物体的生化信息。这种技术最近已被用于研究新生儿脑能量代谢。通过这种方式可以评估高能磷酸代谢和磷脂代谢，并可建立与癫痫发作或与磷酸肌酸：正磷酸盐比率降低相关的长期神经后遗症等方面的现有临床关联。新生儿MRS的未来趋势将提供有关脑形态和代谢发育的更多信息。
