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一名73岁男性的原发性肾尤文肉瘤

Primary Ewing's Sarcoma of the Kidney in a 73-Year-Old Man.

作者信息

Wedde T B, Lobmaier I V K, Brennhovd B, Lohne F, Hall K S

机构信息

Department of Oncology, The Norwegian Radium Hospital, Oslo University Hospital, P.O. Box 4953 Nydalen, 0424 Oslo, Norway.

出版信息

Sarcoma. 2011;2011:978319. doi: 10.1155/2011/978319. Epub 2011 Jun 7.

Abstract

Objective. Ewing's sarcoma of the kidney is rare and is usually found in young adults. We present here a single case study of Ewing's sarcoma found in an elderly man. Material and methods. A 73-year-old man underwent routine surgery for hydrocoele of the testis. He developed urinary obstruction symptoms, and radiological examinations revealed a tumour in the right kidney. Results. Microscopical, immunohistochemical, and molecular pathological analysis of the tumour was consistent with Ewing's sarcoma. FISH showed rearrangement of chromosomes 22q12 (EWSR1). The patient subsequently underwent nephrectomy followed by 6 adjuvant chemotherapy cycles. Follow-up after 7 months shows no recurrence. Conclusion. This case report presents not only the rare finding of Ewing's sarcoma in the kidney, but also the occurrence of this tumour entity in an elderly patient. Treatment options for the different types of renal tumours are vastly different and the need for a correct diagnosis is, therefore, vital.

摘要

目的。肾尤文肉瘤罕见,通常见于年轻成年人。我们在此呈现一例在老年男性中发现的尤文肉瘤的个案研究。材料与方法。一名73岁男性因睾丸鞘膜积液接受常规手术。他出现了尿路梗阻症状,影像学检查显示右肾有一个肿瘤。结果。对肿瘤进行的显微镜检查、免疫组化和分子病理分析与尤文肉瘤相符。荧光原位杂交显示22q12(EWSR1)染色体重排。患者随后接受了肾切除术,接着进行了6个周期的辅助化疗。7个月后的随访显示无复发。结论。本病例报告不仅展示了肾尤文肉瘤这一罕见发现,还呈现了该肿瘤实体在老年患者中的发生情况。不同类型肾肿瘤的治疗方案差异巨大,因此正确诊断至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0302/3137979/9163a7c86195/SRCM2011-978319.001.jpg

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