Zheng Li-Wei, Wang Qi, Zhou Xue-Dong
State Key Laboratory of Oral Diseases, Sichuan University, Chengdu 610041, China.
Hua Xi Kou Qiang Yi Xue Za Zhi. 2011 Jun;29(3):334-7.
Over the last decade, as tremendous innovations have been achieved in scientific technology, translational medicine has come into the focus of academic medicine, and significant intellectual and financial efforts have been made to initiate a multitude of bench-to-bedside projects. The concept of translational medicine is described as the transfer of new understandings of disease mechanisms gained in the laboratory into the development of new methods for diagnosis, therapy, and prevention and their first testing in humans, meanwhile, translational medicine also is described as a patient-oriented population research and the translation of results from clinical studies into everyday clinical practice and health decision making. Translational medicine is a hot spot in recent academic field, and it is crucial for improving the living standard of population and renewing the research idea and technology. It has, however, significant obstacles during the approach of translational medicine. We here review the background, concept, current situation of translational dental medicine, key components and obstacles of translational medicine.
在过去十年中，随着科学技术取得了巨大创新，转化医学已成为学术医学的焦点，人们在智力和财力方面做出了巨大努力，启动了众多从实验室到临床的项目。转化医学的概念被描述为将在实验室中获得的对疾病机制的新认识转化为新的诊断、治疗和预防方法的开发及其在人体中的首次测试，同时，转化医学也被描述为以患者为导向的群体研究以及将临床研究结果转化为日常临床实践和健康决策。转化医学是当前学术领域的一个热点，对于提高人群生活水平以及更新研究理念和技术至关重要。然而，在转化医学的推进过程中存在重大障碍。我们在此回顾转化牙医学的背景、概念、现状、转化医学的关键组成部分和障碍。
