Biomaterials, Biomimetics & Biophotonics, King's College London Dental Institute at Guy's, King's College and St. Thomas' Hospitals, Floor 17 Guy's Hospital, London SE1 9RT, UK.
J Dent. 2010 May;38(5):411-22. doi: 10.1016/j.jdent.2010.01.010. Epub 2010 Feb 2.
The exposure of dentinal tubules causes fluid movement and dentinal hypersensitivity. This study aimed at evaluating the dentine permeability after prophylactic measures performed on exposed dentine after immersion in artificial saliva and citric acid challenge. Confocal microscopy was performed to evaluate the percentage of occluded tubules (OCT%) and the changes in dentine morphology.
Prophy-powders and pastes were tested in this study. An oxalic acid liner was used as a positive control. Dentine discs from human third molars were treated with each material and the dentine permeability was evaluated using a fluid filtration system working at 20cm H(2)O. Artificial saliva and citric acid were used for the determination of changes in dentine permeability. The percentage of tubule occlusion capability (OCT%) was evaluated using confocal microscopy.
All the products used in this study were able to significantly reduce the dentine permeability of acid-etched specimens. The use of the bioactive glass and sodium bicarbonate showed the highest values in dentine permeability reduction. However, the air-polishing procedures performed with Sylc bioactive glass powder created a dentine surface resistant to citric acid attack.
Bioactive glass is suitable for treatment of dentinal hypersensitivity by creating a dentine surface resistant to citric acid attack.
牙本质小管暴露会导致液体流动和牙本质过敏。本研究旨在评估在人工唾液浸泡和柠檬酸刺激后暴露牙本质进行预防性处理后牙本质的渗透性。共聚焦显微镜用于评估封闭小管的百分比(OCT%)和牙本质形态的变化。
本研究测试了预防性粉末和糊剂。草酸衬垫被用作阳性对照。用人的第三磨牙制备牙本质圆盘,并用每种材料处理,并使用在 20cm H 2 O 下工作的液体过滤系统评估牙本质渗透性。人工唾液和柠檬酸用于确定牙本质渗透性的变化。使用共聚焦显微镜评估小管封闭能力的百分比(OCT%)。
本研究中使用的所有产品均能显著降低酸蚀标本的牙本质渗透性。使用生物活性玻璃和碳酸氢钠显示出降低牙本质渗透性的最高值。然而,使用 Sylc 生物活性玻璃粉末进行的空气抛光程序在牙本质表面创造了一种抵抗柠檬酸攻击的特性。
生物活性玻璃通过在牙本质表面形成抵抗柠檬酸攻击的特性,适合治疗牙本质过敏。