Huang Daixin, Shi Shaoxing, Zhu Chuanhong, Yi Shaohua, Ma Wei, Wang Haisheng, Li Huamin
Faculty of Forensic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
J Forensic Sci. 2011 Sep;56(5):1340-2. doi: 10.1111/j.1556-4029.2011.01830.x. Epub 2011 Jul 21.
The male-specific, human Y-chromosomal short tandem repeats (Y-STRs) are very useful in forensic analysis and human evolution studies. The authors report two sexual crime cases in which the perpetrators were successfully traced using Y-haplotype screening of local patrilineages followed by autosomal STR typing. First, several main local patrilineages from local cases were investigated using Y-STR haplotyping, aimed to find the pedigrees whose haplotypes were identical or similar to those of the crime scene samples. Then, several key suspects were defined from the screened pedigrees, and autosomal STR typing was performed to identify the perpetrator of the crime. The application of Y-haplotype screening of local patrilineages followed by autosomal STR typing in these two cases demonstrates its usefulness for solving sexually related crimes in certain populations.
男性特有的人类Y染色体短串联重复序列（Y-STRs）在法医分析和人类进化研究中非常有用。作者报告了两起性犯罪案件，其中通过对当地父系谱系进行Y单倍型筛查，然后进行常染色体STR分型，成功追踪到了犯罪者。首先，使用Y-STR单倍型分型对当地案件中的几个主要当地父系谱系进行了调查，目的是找到单倍型与犯罪现场样本相同或相似的谱系。然后，从筛选出的谱系中确定了几个关键嫌疑人，并进行了常染色体STR分型以识别犯罪者。在这两起案件中，先对当地父系谱系进行Y单倍型筛查，然后进行常染色体STR分型，这证明了其在解决某些人群中性相关犯罪方面的有用性。
