St John of God Healthcare, Richmond Hospital 177 Grose Vale Rd North Richmond, NSW 2754, Australia.
BMC Psychiatry. 2011 Jul 22;11:115. doi: 10.1186/1471-244X-11-115.
The physical wellbeing of people with mental health conditions can often be overlooked in order to treat the primary mental health condition as a priority. Exercise however, can potentially improve both the primary psychiatric condition as well as physical measures that indicate risk of other conditions such as diabetes mellitus and cardiovascular disease. Evidence supports the role of exercise as an important component of treatment for depression and anxiety, yet no randomised controlled trials (RCT's) have been conducted to evaluate the use of exercise in the treatment of people with post traumatic stress disorder (PTSD). This RCT will investigate the effects of structured, progressive exercise on PTSD symptoms, functional ability, body composition, physical activity levels, sleep patterns and medication usage.
Eighty participants with a Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) diagnosis of PTSD will be recruited. Participants will have no contraindications to exercise and will be cognitively able to provide consent to participate in the study. The primary outcome measures will be PTSD symptoms, measured through the PTSD Checklist Civilian (PCL-C) scale. Secondary outcome measures will assess depression and anxiety, mobility and strength, body composition, physical activity levels, sleep patterns and medication usage. All outcomes will be assessed by a health or exercise professional masked to group allocation at baseline and 12 weeks after randomisation. The intervention will be a 12 week individualised program, primarily involving resistance exercises with the use of exercise bands. A walking component will also be incorporated. Participants will complete one supervised session per week, and will be asked to perform at least two other non-supervised exercise sessions per week. Both intervention and control groups will receive all usual non-exercise interventions including psychotherapy, pharmaceutical interventions and group therapy.
This study will determine the effect of an individualised and progressive exercise intervention on PTSD symptoms, depression and anxiety, mobility and strength, body composition, physical activity levels, sleep patterns and medication usage among people with a DSM-IV diagnosis of PTSD.
ACTRN12610000579099.
为优先治疗主要心理健康问题，人们常常忽视心理健康问题患者的身体健康。然而，运动可能会改善主要精神疾病状况以及表明其他疾病（如糖尿病和心血管疾病）风险的身体指标。有证据表明，运动是治疗抑郁症和焦虑症的重要组成部分，但尚未进行随机对照试验（RCT）来评估运动在创伤后应激障碍（PTSD）患者治疗中的作用。这项 RCT 将研究结构化、渐进式运动对 PTSD 症状、功能能力、身体成分、身体活动水平、睡眠模式和药物使用的影响。
将招募 80 名符合《精神疾病诊断与统计手册》（DSM-IV）PTSD 诊断的参与者。参与者无运动禁忌，且认知能力能够同意参与研究。主要结局指标将是 PTSD 症状，通过 PTSD 检查表平民版（PCL-C）量表进行评估。次要结局指标将评估抑郁和焦虑、移动和力量、身体成分、身体活动水平、睡眠模式和药物使用。所有结果将由一名健康或运动专业人员在基线和随机分组后 12 周进行评估，评估人员对分组情况不知情。干预措施将是为期 12 周的个体化方案，主要包括使用运动带进行阻力运动。还将纳入步行部分。参与者将每周完成一次监督课程，并被要求每周至少进行两次其他非监督运动课程。干预组和对照组都将接受所有常规的非运动干预，包括心理治疗、药物干预和小组治疗。
这项研究将确定个体化和渐进式运动干预对 PTSD 症状、抑郁和焦虑、移动和力量、身体成分、身体活动水平、睡眠模式和药物使用的影响在符合 DSM-IV 诊断的 PTSD 患者中。
ACTRN12610000579099。
