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移民糖尿病患者与西班牙出生的糖尿病患者之间是否存在临床和代谢差异?

[Are there any clinical and metabolic differences between immigrant and Spanish-born diabetic patients?].

作者信息

Ortega Sánchez Guacimara, Torres Baile José Luis, Salinas Amirola Itziar, Cortés Béjar Mario

机构信息

Centro de Salud Rodríguez Paterna, Logroño, La Rioja, España.

出版信息

Aten Primaria. 2012 Apr;44(4):209-15. doi: 10.1016/j.aprim.2011.03.004. Epub 2011 Jul 21.

DOI:10.1016/j.aprim.2011.03.004
PMID:21777995
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7025248/
Abstract

AIM

To determine the clinical features and the metabolic control in immigrant diabetic patients in two Primary Care centres in La Rioja, Spain.

DESIGN

Descriptive study.

SETTING

Two urban Primary Care centres which cover a population of 11,700 and 23,000 patients in Logroño.

PRIMARY OUTCOMES

Socio-demographic variables (age, sex, origin country of origin, age at onset of diabetes), clinical variables (blood pressure, waist circumference (WC), high, weight, BMI) and analytical variables (fasting blood glucose, HbA1c, lipid profile). The immunology of DM and baseline C-peptide were studied in patients younger than 40 years old.

PARTICIPANTS

A total of 70 diabetic immigrants, aged between 18 and 70 years old and registered until December 31(st) 2009, and 70 Spanish-born diabetic patients were selected by consecutive sampling.

RESULTS

The final sample consisted of 140 patients (70 immigrants, 70 Spanish). Mean age of Spanish-born diabetics, 55.5 years, of immigrants 45.7 years (P=.002).Age at diagnosis 38.4 years in immigrants and 48.1 years in autochthonous (P=.004).WC in immigrants 104.1cm, in Spanish-born, 105.3 cm (P=.56).BMI in immigrants 29, in Spanish-born 32.1 (P=.06).Mean glycated haemoglobin (HbA1c) in immigrants 8.4%, in Spanish-born 7.5% (P=.002). Blood pressure and lipid values were lower in Hindustani and North African patients than in Spanish-born and other immigrant groups.

CONCLUSIONS

Immigrant diabetic patients are younger at diagnosis, have an unchanged baseline C-peptide secretion, higher HbA1c levels, higher WC with lower BMI compared to Spanish-born patients.

摘要

目的

确定西班牙拉里奥哈两个初级保健中心的移民糖尿病患者的临床特征和代谢控制情况。

设计

描述性研究。

地点

两个城市初级保健中心,在洛格罗尼奥分别覆盖11,700名和23,000名患者。

主要结局

社会人口统计学变量(年龄、性别、原籍国、糖尿病发病年龄)、临床变量(血压、腰围(WC)、身高、体重、体重指数)和分析变量(空腹血糖、糖化血红蛋白(HbA1c)、血脂谱)。对40岁以下患者研究了糖尿病免疫学和基线C肽。

参与者

通过连续抽样选取了70名年龄在18至70岁之间且截至2009年12月31日登记在册的移民糖尿病患者,以及70名西班牙出生的糖尿病患者。

结果

最终样本包括140名患者(70名移民,70名西班牙人)。西班牙出生的糖尿病患者平均年龄为55.5岁,移民为45.7岁(P = 0.002)。移民的诊断年龄为38.4岁,本地人为48.1岁(P = 0.004)。移民的腰围为104.1厘米,西班牙出生的为105.3厘米(P = 0.56)。移民的体重指数为29,西班牙出生的为32.1(P = 0.06)。移民的平均糖化血红蛋白(HbA1c)为8.4%,西班牙出生的为7.5%(P = 0.002)。印度斯坦和北非患者的血压和血脂值低于西班牙出生者和其他移民群体。

结论

与西班牙出生的患者相比,移民糖尿病患者诊断时更年轻,基线C肽分泌不变,糖化血红蛋白水平更高,腰围更大但体重指数更低。

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