Department of Oral and Maxillofacial Surgery, Yamaguchi University Graduate School of Medicine, 1-1-1 Minamikogushi, Ube, Japan.
Dent Mater J. 2011;30(4):431-7. doi: 10.4012/dmj.2010-162. Epub 2011 Jul 21.
It has previously been demonstrated that apatite may be coated on the surface of titanium (Ti) at room temperature when the titanium is blasted with apatite powder. This method is known as the blast coating (BC) method. In this study, the osteoconductivity and tissue response to Ti implants blast-coated with apatite (BC implants) were evaluated using apatite-coated Ti implants produced using the flame spraying (FS) method (FS implants) and pure Ti implants as a control. Initial evaluation using simulated body fluid demonstrated higher osteoconductivity in BC implants than in FS implants. Therefore, specimens were implanted in rat tibias for 1, 3 and 6 weeks. At one week after implantation, BC implants showed much higher bone contact ratio when compared with FS implants; the bone contact ratio of BC implants was 75.7%, while the FS and pure Ti implants had ratios of 30.8% and 5.5%, respectively. The difference in bone contact ratio between BC and FS implants decreased with implantation time and the ratios were equal after 6 weeks. In conclusion, BC implants show higher osteoconductivity than FS implants, and thus BC implants are beneficial for early fixation of implants to bone tissue.
先前已经证明,当钛用磷灰石粉末喷射时,磷灰石可以在室温下覆盖在钛的表面上。这种方法被称为喷涂层(BC)方法。在这项研究中,使用火焰喷涂(FS)方法(FS 植入物)产生的磷灰石涂层钛植入物(FS 植入物)和纯钛植入物作为对照,评估了用磷灰石(BC 植入物)涂覆的钛植入物的骨传导性和组织反应。使用模拟体液的初步评估表明,BC 植入物的骨传导性高于 FS 植入物。因此,将标本植入大鼠胫骨 1、3 和 6 周。植入后一周,BC 植入物的骨接触率明显高于 FS 植入物;BC 植入物的骨接触率为 75.7%,而 FS 和纯钛植入物的骨接触率分别为 30.8%和 5.5%。BC 和 FS 植入物之间的骨接触率差异随着植入时间的延长而减小,6 周后两者相等。总之,BC 植入物比 FS 植入物具有更高的骨传导性,因此 BC 植入物有利于植入物早期固定在骨组织上。