用于正电子发射断层扫描/荧光双模成像的 bodipy 染料的快速水相 [18F]-标记。
Rapid aqueous [18F]-labeling of a bodipy dye for positron emission tomography/fluorescence dual modality imaging.
机构信息
Molecular Imaging Center, Department of Radiology, University of Southern California, Los Angeles 90033, USA.
出版信息
Chem Commun (Camb). 2011 Sep 7;47(33):9324-6. doi: 10.1039/c1cc13089g. Epub 2011 Jul 21.
PMID:21779546
Abstract
We report the rapid nucleophilic [(18)F]-radiolabeling of a bodipy dye in aqueous solutions. This radiolabeled dye, whose biodistribution and clearance has been studied in mice, is stable in vivo and can be used as a positron emission tomography/fluorescence dual modality imaging agent.
摘要
我们报告了一种 bodipy 染料在水溶液中快速亲核 [(18)F]-放射性标记。这种放射性标记的染料已在小鼠中进行了生物分布和清除研究，在体内稳定，可以用作正电子发射断层扫描/荧光双模成像剂。
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