突尼斯自身免疫性大疱性皮肤病谱：一项 11 年的研究及文献复习。
Spectrum of autoimmune blistering dermatoses in Tunisia: an 11-year study and a review of the literature.
机构信息
Dermatology Department, La Rabta Hospital, Jabbari, Bab Saadoun, Tunis, Tunisia.
出版信息
Int J Dermatol. 2011 Aug;50(8):939-44. doi: 10.1111/j.1365-4632.2010.04801.x.
BACKGROUND
Autoimmune bullous dermatoses (ABD) are a rare but significant group of cutaneous disorders posing great diagnostic and therapeutic challenges to the treating dermatologist. Few surveys have been carried out to describe the whole spectrum of ABD in a region.
OBJECTIVE
To determine the clinicoepidemiological features of various ABD.
METHODS
We retrospectively recruited all ABD cases seen during an 11-year period (1997-2007).
RESULTS
One hundred and seventy-four patients were involved (16.3 cases/year). Pemphigus was observed to be the most common ABD (53%), with the majority being pemphigus vulgaris (61%) vs. 36% of pemphigus foliaceus (Tunisian pemphigus).
DISCUSSION
Most epidemiological surveys have focused on a single or just one group of ABD. In our series, pemphigus foliaceus was relatively more prevalent than in occidental data. The frequencies of subepidermal immunobullous dermatoses in our study were in agreement with those in the literature.
背景
自身免疫性大疱性皮肤病（ABD）是一组罕见但严重的皮肤疾病，对治疗皮肤科医生构成了巨大的诊断和治疗挑战。很少有调查来描述一个地区的 ABD 全貌。
目的
确定各种 ABD 的临床流行病学特征。
方法
我们回顾性地招募了在 11 年期间（1997-2007 年）观察到的所有 ABD 病例。
结果
共有 174 例患者参与（16.3 例/年）。天疱疮是最常见的 ABD（53%），其中大多数为寻常型天疱疮（61%），而落叶型天疱疮（36%）（突尼斯天疱疮）。
讨论
大多数流行病学调查都集中在单一或一组 ABD 上。在我们的研究中，落叶型天疱疮比西方数据更为常见。我们研究中表皮下水疱性皮肤病的频率与文献中的一致。
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