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[Studies on the chemical constituents of Brucea javanica (L.) Merr].

作者信息

Yu Y N, Li X

机构信息

Shenyang College of Pharmacy.

出版信息

Yao Xue Xue Bao. 1990;25(5):382-6.

PMID:2178313
Abstract

An alkaloid and a quassinoid were isolated from the fruit of Brucea javanica (L.) Merr, and were identified as 4-ethoxycarbonyl-2-quinolone (1) and bruceine I (2). Compound 1 was found from natural resource for the first time. The structure of the new compound 2 was elucidated on the basis of spectral data and chemical evidence. Three well known compounds vanillic acid (3), quercetin-3-O-beta-D-galactoside (4), and luteolin-7-O-beta-D-glucoside (5) were also isolated. All of them were first reported to occur in the Brucea genus.

摘要

相似文献

1
[Studies on the chemical constituents of Brucea javanica (L.) Merr].
Yao Xue Xue Bao. 1990;25(5):382-6.
2
New quassinoids, javanicolides C and D and javanicosides B--F, from seeds of Brucea javanica.从鸦胆子种子中分离得到的新苦木素类化合物——鸦胆子苦素C和D以及鸦胆子苷B - F 。
J Nat Prod. 2004 May;67(5):863-8. doi: 10.1021/np030484n.
3
Yadanzioside P, a new antileukemic quassinoid glycoside from Brucea javanica (L.) Merr with the 3-O-(beta-D-glucopyranosyl)bruceantin structure.鸦胆子苷P,一种来自鸦胆子(Brucea javanica (L.) Merr)的具有3 - O -(β - D - 吡喃葡萄糖基)鸦胆子丁结构的新型抗白血病苦木素苷。
Chem Pharm Bull (Tokyo). 1986 Oct;34(10):4447-50. doi: 10.1248/cpb.34.4447.
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In vitro antitrypanosomal activities of quassinoid compounds from the fruits of a medicinal plant, Brucea javanica.药用植物鸦胆子果实中苦木素类化合物的体外抗锥虫活性
Vet Parasitol. 2008 Dec 20;158(4):288-94. doi: 10.1016/j.vetpar.2008.09.021. Epub 2008 Sep 26.
5
Bruceosides D, E, and F, three new cytotoxic quassinoid glucosides from Brucea javanica.鸦胆子苷D、E和F,从鸦胆子中分离得到的三种新的具有细胞毒性的苦木素类糖苷。
J Nat Prod. 1995 Jul;58(7):1032-8. doi: 10.1021/np50121a007.
6
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[Studies on the chemical components of Brucea javanica].[鸦胆子化学成分的研究]
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Yakugaku Zasshi. 1990 Nov;110(11):834-8. doi: 10.1248/yakushi1947.110.11_834.

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A review of : metabolites, pharmacology and clinical application.综述:代谢物、药理学与临床应用
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Bruceine D inhibits Cell Proliferation Through Downregulating LINC01667/MicroRNA-138-5p/Cyclin E1 Axis in Gastric Cancer.鸦胆子素D通过下调LINC01667/微小RNA-138-5p/细胞周期蛋白E1轴抑制胃癌细胞增殖。
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