Department of Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Osaka, Japan.
J Thorac Cardiovasc Surg. 2012 May;143(5):1007-13. doi: 10.1016/j.jtcvs.2011.06.024. Epub 2011 Jul 23.
For aortic arch aneurysms, conventional total arch replacement has been the standard surgical option. In selected high-risk patients, we have attempted less invasive hybrid procedure involving supra-aortic bypass and endovascular stent-graft placement. We review the early and midterm outcomes to clarify the impact of the hybrid procedure.
Between October 2007 and December 2010, 27 patients were treated with the hybrid procedure. During the same period, 191 patients underwent elective conventional total arch replacement. On retrospective analysis, the hybrid procedure was feasible in 103 patients (hybrid feasible) and not feasible in 88 patients (hybrid impossible). Patients undergoing the hybrid procedure attained significantly higher additive (11.6 ± 2.2 vs 9.5 ± 2.4, 10.3 ± 2.8, P < .001, P = .044) and logistic (31.1 ± 14.1 vs 18.8 ± 12.6, 23.7 ± 16.0, P < .001, P = .047) European System for Cardiac Operative Risk Evaluation scores than hybrid-feasible and hybrid-impossible groups.
Although the patients in the hybrid group had significantly higher risk, the early outcomes including mortality and morbidity were similar among the 3 groups, as were the 2-year survivals during the follow-up period: 85.9% for the hybrid group, 89.6% for the hybrid-feasible group, and 86.7% for the hybrid-impossible group (P = .510, .850, log-rank test). In the hybrid group, 2 patients required reintervention for type I endoleak.
The early and midterm outcomes of the hybrid procedure for aortic arch aneurysms were satisfactory. This procedure has the potential to be an alternative for conventional total arch replacement for high-risk patients.
对于主动脉弓动脉瘤,传统的全弓置换术一直是标准的手术选择。在一些高危患者中,我们尝试了一种微创的杂交手术,包括主动脉弓上旁路和血管内支架移植。我们回顾了早期和中期结果,以明确杂交手术的影响。
2007 年 10 月至 2010 年 12 月期间,27 例患者接受了杂交手术治疗。同期,191 例患者接受了选择性常规全弓置换术。在回顾性分析中,杂交手术在 103 例患者中可行(杂交可行),在 88 例患者中不可行(杂交不可行)。接受杂交手术的患者获得了显著更高的附加(11.6 ± 2.2 与 9.5 ± 2.4、10.3 ± 2.8,P <.001,P =.044)和逻辑(31.1 ± 14.1 与 18.8 ± 12.6、23.7 ± 16.0,P <.001,P =.047)欧洲心脏手术风险评估系统评分,而杂交可行和杂交不可行组之间的差异有统计学意义。
尽管杂交组患者的风险显著较高,但早期结果包括死亡率和发病率在 3 组之间相似,随访期间 2 年生存率也相似:杂交组为 85.9%,杂交可行组为 89.6%,杂交不可行组为 86.7%(P =.510,.850,对数秩检验)。在杂交组中,有 2 例患者需要再次介入治疗 I 型内漏。
主动脉弓动脉瘤杂交手术的早期和中期结果令人满意。对于高危患者,该手术可能是传统全弓置换术的替代方法。