Istanbul Technical University, Faculty of Science and Letters, Department of Chemistry, Maslak, Istanbul, Turkey.
Colloids Surf B Biointerfaces. 2011 Nov 1;88(1):265-70. doi: 10.1016/j.colsurfb.2011.06.042. Epub 2011 Jul 7.
Polysulfone/poly(ethylene glycol) amphiphilic networks were prepared via in situ photo-induced free radical crosslinking polymerization. First, the hydrophobic polysulfone diacrylate (PSU-DA) oligomer was synthesized by condensation polymerization and subsequent esterification processes. Then, the obtained oligomer was co-crosslinked with the hydrophilic poly(ethylene glycol) diacrylate (PEG-DA) or poly(ethylene glycol) methyl ether acrylate (PEG-MA) at different feed ratios. In the case of PEG-MA, the resulting network possessed dangling pendant hydrophilic chains on the crosslinked surface. The structure and the morphology of the membranes were characterized by attenuated total reflection infrared spectroscopy (ATR-IR) and scanning electron microscopy (SEM). The enhancement of surface hydrophilicity was investigated by water contact angle measurements. The biomolecule adsorption properties of these networks were also studied. The biomolecules easily adsorbed on the surface of the hydrophobic polysulfone networks whereas dangling hydrophilic chains on the surface prevented the adsorption of the biomolecules.
通过原位光引发自由基交联聚合制备了聚砜/聚乙二醇两亲网络。首先，通过缩聚和随后的酯化过程合成疏水性聚砜二丙烯酸酯（PSU-DA）低聚物。然后，所得低聚物与亲水性聚乙二醇二丙烯酸酯（PEG-DA）或聚乙二醇甲基醚丙烯酸酯（PEG-MA）以不同的进料比进行共交联。在 PEG-MA 的情况下，所得网络在交联表面具有悬垂的亲水性链。通过衰减全反射红外光谱（ATR-IR）和扫描电子显微镜（SEM）对膜的结构和形态进行了表征。通过水接触角测量研究了表面润湿性的增强。还研究了这些网络的生物分子吸附性能。生物分子容易吸附在疏水性聚砜网络的表面上，而表面上悬垂的亲水性链阻止了生物分子的吸附。
