Laboratory of Biocatalysis and Synthetic Biotechnology, State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, People's Republic of China.
Curr Opin Biotechnol. 2011 Dec;22(6):784-92. doi: 10.1016/j.copbio.2011.07.002. Epub 2011 Jul 23.
Various biocatalytic methods have been developed for the synthesis of chiral chemicals, which have made their synthesis more environmentally friendly and product-specific. New opportunities for biocatalysis, including new scientific developments in genomics and protein engineering technologies, novel process developments and the increased availability of useful enzymes, offer many possibilities for the manufacture of new chiral compounds and deliver greener and economically competitive processes. In this review, new opportunities for biocatalysis in the preparation of chiral molecules are outlined and highlighted.
各种生物催化方法已经被开发出来用于手性化学品的合成，这使得它们的合成更加环保和具有产物特异性。生物催化的新机会，包括基因组学和蛋白质工程技术方面的新科学进展、新颖的工艺开发以及更多有用酶的可用性，为新的手性化合物的制造提供了许多可能性，并带来了更环保和经济竞争力的工艺。在这篇综述中，概述并强调了生物催化在手性分子制备方面的新机会。
