Department of Ophthalmology, Tsukazaki Hospital, Himeji, 68-1 Waku, Aboshi-ku, Himeji-City, Hyogo 671-1227, Japan.
Can J Ophthalmol. 2011 Jun;46(3):242-6. doi: 10.1016/j.jcjo.2011.05.015. Epub 2011 May 27.
To investigate the relationship between the biophysical properties of the cornea and eye on the intraocular pressure (IOP) and ocular pulse amplitude (OPA) before and after cataract surgery.
Intervention study.
The left eyes of 311 patients.
The left eyes of 338 patients undergoing cataract surgery without other eye pathology were studied. IOP and OPA were recorded by dynamic contour tonometry (DCT) 1 week before and 14 weeks after cataract surgery. The axial length, corneal curvature, central corneal thickness, anterior chamber depth, and anterior chamber angle were measured 1 week before cataract surgery. Multiple regression analyses of these factors to the preoperative OPA were performed. The difference between the pre- and postoperative IOP and OPA were investigated by paired t tests.
Three hundred and eleven of 338 eyes were analyzed. The preoperative OPA was negatively correlated with axial length (β = -0.24, p < 0.0001) and positively correlated with the preoperative IOP (β = 0.13, p < 0.0001). The average OPA was significantly decreased after cataract surgery (p < 0.0001). The mean change in postoperative OPA was -0.45 ± 0.63 mm Hg (95% CI -0.52 to -0.38 mm Hg).
The preoperative OPA was negatively correlated with axial length as reported. A significant decrease in OPA was observed after the cataract surgery.
研究白内障术前和术后角膜和眼的生物物理特性与眼内压（IOP）和眼脉冲幅度（OPA）的关系。
干预性研究。
311 例患者的左眼。
研究了 338 例接受白内障手术且无其他眼部疾病的患者的左眼。在白内障手术前 1 周和术后 14 周，通过动态轮廓眼压计（DCT）记录 IOP 和 OPA。在白内障手术前 1 周测量眼轴长度、角膜曲率、中央角膜厚度、前房深度和前房角。对这些因素与术前 OPA 进行多元回归分析。通过配对 t 检验研究术前和术后 IOP 和 OPA 的差异。
对 338 只眼中的 311 只进行了分析。术前 OPA 与眼轴长度呈负相关（β = -0.24，p < 0.0001），与术前 IOP 呈正相关（β = 0.13，p < 0.0001）。白内障手术后 OPA 明显降低（p < 0.0001）。术后 OPA 的平均变化为-0.45 ± 0.63 mmHg（95%CI -0.52 至-0.38 mmHg）。
正如报道的那样，术前 OPA 与眼轴长度呈负相关。白内障手术后 OPA 明显降低。
