INSERM, U848 'Apoptosis, Cancer and Immunity', Villejuif, France.
EMBO J. 2011 Jul 22;30(16):3213-4. doi: 10.1038/emboj.2011.244.
The precise mechanisms by which autophagy participates in the control of intracellular infection have only lately begun to emerge. In a recent issue of , Wild demonstrate how innate immunity and autophagy cooperate in the clearance of cytosolic , thereby shedding new light on the molecular regulation of xenophagy.
自噬参与细胞内感染控制的确切机制最近才开始显现。在最近一期的《自然免疫学》杂志上,Wild 等人证明了先天免疫和自噬如何协同清除细胞质中的 ,从而为异噬作用的分子调控提供了新的线索。